501例乳腺癌围手术期患者中医证候分布规律的临床研究  

Clinical Study on the Distribution Pattern of TCM Syntromes in 501 Breast Cancer Patients During Perioperative Period

作　　者：司徒红林[1] 陈前军[1] 李娟娟[2] 刘晓雁[1] 朱华宇[1] 郭莉[1] 林毅[1] 刘鹏熙[1] 

机构地区：[1]广州中医药大学附属广东省中医院乳腺科,广东广州510120 [2]广州中医药大学

出　　处：《辽宁中医杂志》2010年第4期595-598,共4页Liaoning Journal of Traditional Chinese Medicine

基　　金：上海颜德馨中医药基金会科学研究基金课题(05-013)

摘　　要：目的:探讨乳腺癌围手术期中医证候分布规律,为制定乳腺癌围手术期辨证分型标准奠定基础。方法:对501例乳腺癌围手术期患者采用文献调研、设计临床证候信息采集表,运用聚类分析方法得出各证型诊断依据。结果:聚三类较切合临床实际。经专家讨论确定各证型名称是:术前1天为肝郁痰凝兼肾虚,肝郁血瘀及冲任失调兼肝郁;术后第1天为脾胃虚弱,气阴两虚,湿困脾胃;术后第3天为脾胃虚弱,湿困脾胃,气血两虚;术后第6天为脾胃虚弱,气阴两虚,湿困脾胃。结论:初步制定乳腺癌围手术期中医辨证分型标准,术前以实证为主,术后以虚证为主。可供临床诊断与疗效评价之参考。Objective：To probe the distribution pattern of TCM Syntromes of breast cancer patieints in perioperative period,and estabilsh a foundation for developing Symdrome Differentiated standard for it.Methods：Reasearching on 501 patients with breast cancer in periopreative period by clustering analysis on clinical Syntromes,then come to the diagnosiic basis.Results：The Syntromes are most practical to be clustered into 3 classes： in the day before surgery,they are liver Qi depression and phlegm stasis with kidney difciency,liver Qi depression with blood stasis,and disproportion of Chu and Ren meridian with liver Qi depression;in the day after surgery,they are hypofunctioning of spleen and stomach,deficiency of both Qi and blood and dampness disturbing spleen and stomach;in third day after surgery,they are hypofunctioning of spleen and stomach,deficiency of both Qi and Yin,or dampness disturbing spleen and stomach.Conclusion：The symdrome differentiated standard for perioperative period of breast cancer patients was primarily established and the preoperatively symdrome is suffiency mostly while the postoperatively symdrome is deficiency mostly.This result can be referenced in clinical diagnosis and therapeutic evaluation.

关 键 词：乳腺癌 围手术期 中医证候 聚类分析 

分 类 号：R737.9[医药卫生—肿瘤]