金属烤瓷冠对龈沟液中IL-1β、AST及ALP水平的影响  

Effects of Based Porcelain-Fused–to-Metal Crown on IL-1β, AST and ALP in Gingival Crevicular Fluid

作　　者：赵彤[1] 高平[2] 

机构地区：[1]天津医科大学第二医院口腔科,300211 [2]天津医科大学口腔医院

出　　处：《天津医药》2010年第3期186-188,共3页Tianjin Medical Journal

摘　　要：目的:了解不同金属烤瓷冠对局部牙周组织造成的影响,以及龈沟液中白细胞介素(IL)-1β、天冬氨酸转氨酶(AST)和碱性磷酸酶(ALP)水平与牙周组织健康状况的关系。方法:选择28例接受金属烤瓷冠修复患者的上颌切牙(共34颗)为实验对象,其中镍铬合金烤瓷冠19颗,金铂合金烤瓷冠15颗。以患牙的对侧同名健康牙为对照组,在烤瓷冠戴入6～8个月后复诊,并对龈沟液中IL-1β、AST、ALP水平进行分析。结果:镍铬合金烤瓷组IL-1β及ALP水平均高于对照组,差异有统计学意义;金铂合金烤瓷组IL-1β、ALP与对照组差异无统计学意义;两种金属烤瓷冠AST水平均普遍高于对照组,差异有统计学意义。结论:镍铬合金烤瓷冠对牙周组织的不利影响较明显,而金铂合金烤瓷冠修复前后各项指标变化不明显。龈沟液中IL-1β、AST及ALP的浓度水平可以较敏感地反应金属烤瓷冠对牙周组织的影响。Objective： To detect the effects of porcelain-fused-to-metal （PFM） crown on the periodontal tissue of the restored teeth, and the relationship between the levels of interleukin （IL）-1β, aspartate transaminase （AST） and alkaline phosphatase（ALP） in gingival crevicular fluid（GCF） and the health condition of periodontal tissue. Methods： Among 28 patients, 34 maxillary incisors with PFM crowns were selected for the study. There were 19 Ni-Cr PFM crowns and 15 Au-Pt PFM crowns. The contralateral homonymy natural teeth were healthy and treated as control teeth. The patients were followed up 6 to 8 months after restoring crowns. The values of IL-1β, AST and ALP in GCF were analysed. Results： The concentrations of IL-1β and ALP were significantly higher in GCF of Ni-Cr PFM compared with those of control, whereas no significant difference in Au-Pt PFM group compared with that of control. The level of GCF-AST was higher in Ni-Cr PFM and Au-Pt PFM group than that of healthy control. Conclusion： Ni-Cr PFM crowns have negative influence on periodontal tissue, but Au-Pt PFM have little influence on periodontal tissue of the restored teeth. The activity of IL-1β, AST and ALP of GCF are sensitive to reflect the effect of PFM crowns of different materials on periodontal tissue.

关 键 词：金属烤瓷合金 牙龈缝液 白细胞介素1Β 天冬氨酸氨基转移酶类 碱性磷酸酶 

分 类 号：R783[医药卫生—口腔医学]