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作 者:张春玲[1] 徐忠宝[1] 李继梅[1] 王长英[1] 李伟荣[1] 刘占东[1]
机构地区:[1]首都医科大学附属北京友谊医院神经内科,100050
出 处:《中华神经科杂志》2010年第4期247-250,共4页Chinese Journal of Neurology
摘 要:目的分析纹状体内囊梗死(SCI)的临床和影像特征并探讨其发病机制。方法回顾分析34例SCI患者的临床及影像资料。将患者分为皮质型SCI(CSCI)和非皮质型SCI(NCSCI)2组,进行临床和影像资料的对比分析。结果CSCI23例,NCSCI11例。CT血管成像共检出大脑中动脉和颈内动脉狭窄或闭塞25例。CT脑灌注成像检出26例大脑中动脉供血区内血流灌注减低,其中19例累及广泛的大脑中动脉供血区。CSCI患者中检出上述动脉狭窄或闭塞21例,明显高于NCSCI患者中的4例(x2=3.27,P=0.020),CSCI患者中检出MCA供血区内血流减低区21例,明显高于NCSCI患者中的5例(x2=8.62,P=0.007)。结论SCI有临床和影像特征,大部分由于MCA原位病变所致。动脉病变和其造成的灌注减低是发生皮质症状的重要原因。Objective To study the clinical characteristics and neuroimagings of striatocapsular infarction (SCI) and its pathogenesis. Methods Thirty-four patients with SCI diagnosed by CT and MRI were recruited in this retrospective study, including 23 certical SCI (CSCI) and 11 noncertical SCI (NCSCI). The clinical symptoms and CT angiography (CTA) and CT perfusion (CTP) imagings were reviewed to compare differences between CSCI and NCSCI. Results The CTA showed severe stenosis or occlusion MCA or ICA in 25 cases and CTP showed hypo-perfusion area in MCA territory in 26 cases, of those in 19 cases hypoperfusion involved massive area in MCA territory. The stenosis or occlusion in MCA or ICA and the hypoperfusion area in MCA territory were greater in CSCI patients than in NCSCI patients ( X2 = 3.27 ,P = 0. 020; X2 = 8.62, P = 0. 007 ). Conclusions SCI can be divided into CSCI and NCSCI subgroups. In this study most SCI were caused by occlusive lesion in original segment of MCA. The MCA or ICA lesion and the massive hypo-perfusion in MCA territory arc important causes of cortical symptoms.
分 类 号:R743.3[医药卫生—神经病学与精神病学]
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