脊髓纵裂产前超声诊断并文献回顾  

Prenatal diagnosis of diastematomyelia by ultrasound and review of the literature

作　　者：文华轩[1] 李胜利[1] 陈秀兰[1] 欧阳淑媛[1] 陈琮瑛[1] 姚远[1] 廖玉媚[1] 夏珣[1] 

机构地区：[1]南方医科大学附属深圳市妇幼保健院超声科,深圳518028

出　　处：《中华医学超声杂志（电子版）》2010年第3期21-24,共4页Chinese Journal of Medical Ultrasound(Electronic Edition)

基　　金：国家自然科学基金(60671043);国家"十一五"科技支撑计划(2006BAI05A04)

摘　　要：目的探讨脊髓纵裂的产前超声图像特征。方法对1例怀疑椎管内肿瘤的胎儿行系统产前超声检查,超声诊断为脊髓纵裂,总结胎儿脊髓纵裂产前超声诊断特点,与引产后胎儿的高频超声、X线、MRI及病理解剖进行对比研究,并对脊髓纵裂产前诊断相关文献回顾分析。结果本例脊髓纵裂发生于胸6～9水平,椎管内可见圆形高回声占位病变,脊髓受压分成两半,于远端汇合,相应的椎弓骨化中心明显增宽。脐血染色体核型正常。本例终止妊娠后,标本行产后超声、X线照片、MRI检查及病理解剖,证实产前超声诊断。结论脊髓纵裂有特征性超声表现,产前超声可作出诊断。Objective To investigate the prenatal ultrasonic manifestations of diastematomyelia. Methods A fetus was identified as diastematomyelia after took detailed antenatal ultrasound examination for Suspected intraspinal tumor. The prenatal ultrasonic manifestations of the abnormal spinal anatomy were com- pared with the features of the postnatal high-frequency ultrasound, X-ray, MRI and autopsy examinations. Twenty-five cases of diastematomyelia were reviewed and retrieved by PubMed system. Results In our case, the ultrasonic examination revealed a circular hyper-echogenic mass in the enlarged spinal canal, infe- rior fusion of two longitudinal divisions of the thoracic cord, and the widening ossification center at the T6-3~9 level. The chromosomal analysis on cord blood cell had normal karyotype, which was confirmed by postmor- tem X-ray, MRI and autopsy. Conclusion Diastematomyelia can be prenatally diagnosed due to the charac- teristic ultrasonic features.

关 键 词：产前诊断 超声检查 脊髓纵裂 

分 类 号：R714.5[医药卫生—妇产科学] R445.1[医药卫生—临床医学]