量子点标记技术在肿瘤诊断和治疗中的应用  

Application of quantum dots narkers in neoplasm diagnosis and therapy

作　　者：侯渊涛(综述)[1] 蔡景钰(综述)[1] 王桂珍(审校)[1] 

机构地区：[1]中国医科大学基础医学院病原生物学教研室,沈阳110001

出　　处：《国际肿瘤学杂志》2010年第2期122-125,共4页Journal of International Oncology

摘　　要：量子点（QD）是一种荧光标记物，其研究领域涉及生物医学成像、疾病诊断和细胞生物学。QD独特的光学和电子特性使其用于肿瘤标记的检测和前哨淋巴结（SLN）的定位。在肿瘤的光化学疗法中，将QD与光敏剂相连可使图像更加清晰精确，并能够检测深部组织的肿瘤。将QD与治疗剂连接用于药物释放系统能够更加准确地定位肿瘤组织。基于以上优点，QD将有希望应用于肿瘤的临床诊断和治疗。Quantum dots （QD） are fluorescence labels, whose research fields involve biomedical imaging, disease diagnosis, and cell biology. The special optic qualities and electrical qualities of QD make it useful in tumor markers＇ detection, and localization of sentinel lymph node. In photochemotherapy of tumor, the connection of QD with photosensitizer can make the images clearer,more accurate,and be able to detect tumors in deep tissues. The connection of QD with therapeutical agents for drug delivery systems can make the localization of tumor tissues more accurate. Based on these advantages, QD is likely to be used clinically in tumor diagnosis and therapy.

关 键 词：量子点 肿瘤 诊断 光化学疗法 药物释放系统 

分 类 号：R730.4[医药卫生—肿瘤]