涎腺腺样囊性癌的细针吸取细胞学诊断  

A Cytologic Study of Fine Needle Aspiration of Salivary Gland Neoplasms: Adenoid Cystic Carcinoma

作　　者：马博文[1,2,3] 房新志[1,2,3] 平小佳 

机构地区：[1]新疆医学院附属肿瘤医院细胞学室 [2]乌鲁木齐铁路中心医院病理科 [3]新疆医学院第一附属医院病理科

出　　处：《诊断病理学杂志》1998年第2期77-79,共3页Chinese Journal of Diagnostic Pathology

摘　　要：目的对１１例腺样囊性癌病例进行细针吸取细胞学检查，并分析细胞形态学特点，以取得诊断和鉴别诊断的经验。方法１１例均经外科手术切除和组织学证实，将其细胞学结果和形态表现与组织学对比分析。结果１１例中男性６例，女性５例；８例发生于腮腺，颌下腺与舌下腺各１例，另１例发生于气管。发现球团状排列的上皮细胞团伴有多量的粘多糖基质是其细胞学形态特征，相当于组织学上的筛状排列的结构，细胞学结果是可靠的，但必须与涎腺的多形性腺瘤相鉴别。结论细胞学对腺样囊性癌的诊断结论是准确的，同时对其形态学的研究。Objective To study eleven cases of adenoid cystic carcinoma diagnosed by fine needle aspiration cytology (FNAC) and discuss the cellular morphologic features, diagnostic and differential diagnostic criteria.Methods There were eleven patients, consisting of six males and five females. The sites of origin included parotid gland in 8, submandibular gland in 1, sublingual gland in 1, and trachea in one patient. After initial diagnosis with FNAC, all the patients underwent surgical resections, and histological examinations were made for their specimens.Results The FNAC diagnosis was consistent with the histologic diagnosis. The cytologic findings of adenoid cystic carcinoma are characterized by the dense epithelial cells arranged in global form with abundant mucopolysaccharide stromal material, equivalent to the cribriform arranged structure in histology. FNAC is reliable in diagnosis, however it is necessary to differentiate mainly from pleomorphic adenoma of salivary glands.Conclusions Preoperatively, the use of FNAC to diagnose adenoid cystic carcinoma is of value. The study clearly shows that this technique is useful in guiding the management of adnoid cystic carcinoma.

关 键 词：涎腺肿瘤 腺样囊性癌 细胞学 针吸活检 诊断 

分 类 号：R739.870.4[医药卫生—肿瘤]