32例初发初治晚期恶性肿瘤合并血小板减少临床分析  

Clinical analysis of thirty-two cases of platelet decrease in the patients with initial malignant solid tumor

作　　者：聂磊 王云梅[2] 刘敏 丁海滨 

机构地区：[1]陕西省肿瘤医院内科,陕西西安710061 [2]西安交通大学医学院第一附属医院肿瘤内科,陕西西安710061

出　　处：《现代肿瘤医学》2010年第4期800-802,共3页Journal of Modern Oncology

摘　　要：目的:探讨初发初治晚期恶性实体瘤合并血小板减少的常见病因及其对化疗的影响。方法:对32例初发初治晚期恶性肿瘤合并血小板减少的病因及化疗后的结果进行回顾性分析。结果:32例引起初发初治晚期恶性实体瘤合并血小板减少的病因:脾功能亢进6例,弥散性血管内凝血5例,骨髓增生减低2例,巨核系成熟障碍3例,免疫性因素14例,肿瘤侵犯骨髓2例;其中30例进行了化疗,PR19例,SD 11例。结论:初发初治晚期恶性实体瘤合并血小板减少,大多数可耐受化疗,并从化疗中获益。Objective：To approach the common etiological factor of platelet decrease in the patients with initial malignant solid tumor.Methods：Retrospective analysis of the etiological factors of platelet decrease the patients with initial malignant solid tumor was performed.Results：Among 32 patients 6 cases with hypersplenism,five cases with disseminated intravascular coagulation（DIC）,two cases with bone marrow hyperplasia degraded,three cases with somatic nucleus cells dysmaturity,fourteen cases with influenced by immunity factors,two cases bone marrow were encroached by tumor,PR were achieved in nineteen cases and SD in eleven cases.Conclusion：Most patients can be tolerance for chemo therapy.

关 键 词：恶性肿瘤 血小板减少 化疗 

分 类 号：R730.53[医药卫生—肿瘤]