人眼调节前后眼球形态的磁共振成像初步研究  

The initial study of morphological changes of human eyes before and after accommodation by MRI

作　　者：陈青华[1] 王小兵[2] 刘爱珍[2] 王振常[1] 

机构地区：[1]首都医科大学附属北京同仁医院放射科,100730 [2]北京同仁眼科中心北京市眼科学与视觉科学重点实验室

出　　处：《眼科》2010年第2期97-99,共3页Ophthalmology in China

基　　金：国家自然科学基金资助课题(10772124);首都医学发展科研基金重点支持项目(2005-2029)

摘　　要：目的利用磁共振成像(MRI)探讨人眼调节时的晶状体及相关结构形态变化特点。设计前瞻性研究。研究对象健康志愿者。方法对8例健康志愿者11只正视眼分别在视近状态和视远状态进行MRI检查,对晶状体、前房及眼轴的MRI图像进行测量,调节前后晶状体及相关因素的变化进行配对t检验。主要指标晶状体的厚度、截面积,前房深度及眼轴长度。结果 11只正视眼视远时晶状体厚度、截面积、前房深度、眼轴平均为(3.51±0.20)mm、(22.89±1.82)mm2、(3.54±0.27)mm、(23.91±0.90)mm,视近时平均为(3.73±0.34)mm、(23.17±1.66)mm2、(3.29±0.32)mm、(23.82±1.07)mm,调节前后晶状体厚度、前房深度有显著性差异(t=3.563、P=0.007;t=4.804、P=0.001),晶状体截面积、眼轴差异无显著性(t=1.890、P=0.095;t=0.913、P=0.388),晶状体厚度差、前房深度差差异有显著性(P=0.000)。结论 MRI能反映晶状体在调节状态下的形态特点,有望成为研究人眼调节机制的重要方法之一。Objective To investigate the characteristics of the morphological changes of the lens and related structures of human eyes before and after accommodation by magnetic resonance imaging（MRI）. Design Prospective case series. Participants Healthy volunteers. Methods Eleven eyes of 8 healthy volunteers were measured by MRI before and after accommodation. Main Outcome Measures Thickness and sectional area of lens, anterior chamber depth, axial length. Results The thickness and section area of lens, anterior chamber depth, axial length was 3.51±0.20 mm, 22.89±1.82 mm^2, 3.54±0.27 ram, 23.91±0.90 mm before accommodation, and 3.73± 0.34 mm, 23.17±1.66 mm^2, 3.29±0.32 mm, 23.82±1.07 mm after accommodation. The thickness of lens and anterior chamber depth were significantly higher difference after accommodation（t=3.563, P=0.007; t=4.804, P=0.001 ）. Conclusion As a useful tool of biometric measurement, MRI showed the morphological characteristics of the lens and related structures of human eyes, in an accomodated enviroment, and thus might play an important role in related researches. （Ophthalmol CHN, 2010, 19： 97-99）

关 键 词：晶状体 磁共振成像 调节 眼 

分 类 号：R77[医药卫生—眼科] R445.2[医药卫生—临床医学]