广州市城区2000～2004年儿童恶性肿瘤发病和死亡率分析  

Cancer incidence and mortality of children in urban districts of Guangzhou between 2000 and 2004

作　　者：曹卡加[1,2,3] 刘奕龙[1,3] 马国胜[1,3] 

机构地区：[1]华南肿瘤学国家重点实验室,广东广州510060 [2]中山大学肿瘤防治中心鼻咽癌科,广东广州510060 [3]广州市肿瘤登记处,广东广州510060

出　　处：《癌症》2010年第3期359-362,共4页Chinese Journal of Cancer

基　　金：国家"九五"科技攻关项目(No.96-906-01-01)~~

摘　　要：背景与目的：恶性肿瘤是儿童死亡的主要原因之一。本研究分析广州市儿童肿瘤的发病率,探讨儿童肿瘤的发病规律,为广州市儿童肿瘤的防治研究提供科学依据。方法：收集广州市肿瘤登记处2000-2004年儿童肿瘤的发病资料和死亡资料,统计和分析儿童肿瘤的发病率和死亡率。用卡方检验比较不同年份儿童肿瘤的发病率和各年龄别发病率。结果：2000-2004年,广州市儿童肿瘤的发病率为17.91/10万（其中男性18.92/10万,女性16.70/10万）,死亡率为4.73/10万（其中男性4.65/10万,女性4.83/10万）。儿童肿瘤发病率最高的前3位肿瘤依次为淋巴样白血病、中枢神经系统肿瘤和非霍奇金淋巴瘤。0岁组的发病率为77.52/10万, 1-4岁组为21.49/10万, 5-9岁组为9.66/10万, 10-14岁组为17.11/10万, 4组发病率比较差异有统计学意义（χ^2=307.602,P〈0.001）。结论：淋巴样白血病、中枢神经系统肿瘤和非霍奇金淋巴瘤是广州市儿童最常见的恶性肿瘤。4岁以下的儿童是肿瘤的高发人群。Background and Objective： Cancer is one of the most primary causes of death for children. The study was to analyze the cancer incidence and mortality of children in urban districts of Guangzhou between 2000 and 2004,to explore the incidence regularity of pediatric cancers,and to provide a reference for prevention and treatment of pediatric cancers. Methods： The data of cancer incidence and mortality of children during 2000-2004 were collected from Guangzhou Population-based Cancer Registry,and were calculated and analyzed. Results： The cancer incidence of children between 2000 and 2004 in Guangzhou was 17.91 per 100 000 （18.92 per 100 000 in males,16.70 per 100 000 in females）; the cancer mortality was 4.73 per 100 000 （4.65 per 100 000 in males,4.83 per 100 000 in females）. The incidence of lymphoid leukemia ranked first followed by cancer of central nervous system and non-Hodgkin’s lymphoma. Cancer incidence was 77.52 per 100 000 in children of less than one year old,21.49 per 100 000 in 1-4 years,9.66 per 100 000 in 5-9 years and 17.11 per 100 000 in 10-14 years,with significant difference among the four groups （χ^2=307.602, P0.001）. Conclusions： Lymphoid leukemia,cancer of central nervous system and non-Hodgkin’s lymphoma are the most common cancers in children. The children of 0-4 years old are the population with high cancer incidence.

关 键 词：恶性肿瘤/流行病学 儿童肿瘤 发病率 死亡率 肿瘤登记 广州 

分 类 号：R73-31[医药卫生—肿瘤]