人各种角膜病变内皮细胞核变化的初步观察  

A preliminary observation on nuclear changes of human corneal endothelial cells in different kinds of corneal diseases

作　　者：谢立信[1] 李绍伟[1] 董晓光[1] 袁凤波[1] 

机构地区：[1]山东省医学科学院眼科研究所

出　　处：《中华眼科杂志》1998年第1期19-20,I001,共3页Chinese Journal of Ophthalmology

摘　　要：目的观察不同角膜病变对内皮细胞的影响。方法对９１片穿透性角膜移植术时取下的病变角膜片，用１％茜素红和０．２５％锥蓝对角膜内皮细胞联合染色，生物显微镜观察其内皮细胞的形态及细胞核的变化。结果全部病变角膜片均发现有不同数量的双核和多核内皮细胞。结论在特定的条件下，人眼角膜内皮细胞可能存在较强的分裂能力和生理功能代偿能力。Objective To investigate the influence of different kinds of corneal diseases on corneal endothelial cells. Methods The endothelial cells of 91 corneal buttons obtained at the time of penetrating keratoplasty (PKP) were stained by 1% alizarin red and 0.25% trypan blue and observed under biomicroscope. Results Binuclear and polynuclear endothelial cells were found in every buttons. Conclusion Under special conditions, the human corneal endothelial cells possibly have stronger ability of mitosis and compensation.

关 键 词：角膜病变 内皮细胞 细胞核 

分 类 号：R772.2[医药卫生—眼科]