子宫内膜非典型增生过长24例临床病理分析  

A clinicopathological analysis on 24 cases of endometrial complex hyperplasia with atypical hyperplasia

作　　者：张秀珊[1,2] 陈忠伟[1,2] 张玉兰[1,2] 

机构地区：[1]合肥市第一人民医院病理科 [2]上海肿瘤医院病理科

出　　处：《临床与实验病理学杂志》1998年第5期454-455,I061,共3页Chinese Journal of Clinical and Experimental Pathology

摘　　要：目的：分析子宫内膜复杂性增生过长伴非典型性临床病理特点。方法：对２４例子宫内膜复杂性增生过长伴非典型性子宫内膜进行光镜观察及免疫组化染色。结果：２４例中，４例发展为子宫内膜腺癌，７例痊愈，１０例好转，３例在随访中。内膜癌患者的ＰＣＮＡ检测均为阳性高表达。结论：子宫内膜复杂性增生过长伴非典型性，其病变的发展是双向的，即可癌变，也可逆转。Purpose To analyse clinicopathological characteristic of endometrial complex hyperplasia with atypical hyperplasia. Methods Twenty four cases of endometrial comples hyperplasia with atypical hyperplasia were investigated at the light microscope level and were studied by immunohistochemical techmiques. Results Of 24 cases, 4 cases endometrial carcinoma were progressed, 7 cases cured, 10 cases a change for the better, 3 cases followed up. The positive expessions of PCNA were found in all cases of endometrial carcinoma. Conclusion Development of endometrial complex hyperplasia with atyplasia has two directions. It may become cancer or turn into benign lession. The prognosis is determined by age and immunohistochmical results.

关 键 词：子宫内膜增生 非典型增生 临床病理 癌前病变 

分 类 号：R737.330.2[医药卫生—肿瘤]