肝硬化患者血清中sTNF-R_1及TGF-β_1含量与肝功的关系  

Association between Liver function and serum TGF-β_1 and sTNF-R_1 Concentration of Patients with Liver Cirrhosis

作　　者：赵金玲[1] 王秀洁[1] 

机构地区：[1]哈尔滨医科大学附属第一医院急诊内科,黑龙江哈尔滨150001

出　　处：《中国伤残医学》2010年第2期29-31,共3页Chinese Journal of Trauma and Disability Medicine

摘　　要：探讨乙肝后肝硬化患者血清中sTNF-R1及TGF-β1的水平与肝功之间的关系。选取乙肝后肝硬化患者为实验对象,根据其肝功child-pugh分级将32名患者分为3组,A组11例,B组14例,C组7例,应用ELISA的方法分别测定血清中2者的含量。结果:肝功A、B、C3组之间TGF-β1含量无显著性差异(P>0.05);而sTNF-R1含量在各组之间有显著性差异(P<0.05)。可见,乙肝后肝硬化患者肝功child-pugh分级与TGF-β1无关,与sTNF-R1有关。Objective：To make an inquiry into association between liver function and serum TGF-β1 and sTNF-R1 concentration of patients with liver cirrhosis.choose patients with liver cirrhosis as objective.Methods：According to liver function thirty two patients divided into three groups.One（A） is 11 patients,the other（B） is 14,another（C） is 7.Surrey separately serum TGF-β1 and sTNF-R1 concentration according ELISA methods.Result：Showing no significant difference of serum TGF-β1 concentration in liver function（p0.05）;But showing significant difference of serum sTNF-R1 concentration in liver function（p0.05）;Conclusion：It is clear that liver function of patients with posthepatitic B cirrhosis and serum sTNF-R1 concentration are interrelated.

关 键 词：乙肝 肝硬化 sTNF-R1 TGF-Β1 肝功child-pugh分级 

分 类 号：R575.2[医药卫生—消化系统]