吡柔吡星膀胱灌注预防膀胱癌术后复发  

Irrigation of bladder by perarubicin on preventing carcinoma of bladder postoperative recrudescence

作　　者：樊耘[1] 

机构地区：[1]四川省医学科学院附属四川省人民医院城东病区泌尿外科,成都641400

出　　处：《临床医学》2010年第3期27-28,共2页Clinical Medicine

摘　　要：目的探讨吡柔吡星膀胱内灌注预防膀胱癌术后复发的疗效及安全性。方法52例膀胱癌术后患者分为两组,分别用吡柔吡星（THP组）和卡介苗（BCG组）定期膀胱内灌注,随防13-36个月,观察灌注后肿瘤复发情况及并发症。结果THP组复发率17.9%,不良反应率89.3%;BCG组复发率16.6%,不良反应率79.2%。结论吡柔吡星膀胱灌注预防膀胱癌术后复发有效率与卡介苗相同,是一种安全、有效的药物。Objective To investigate the effect and safety of preventing carcinoma of bladder postoperative recrudescence with irrigation of bladder by perarubicin.Methods Fifty-two cases of carcinoma of bladder postoperation were divided into THP group and BCG group,each irrigated regularly with perarubicin and BCG respectively with 13-36 months follow-up.After irrigation,tumor recrudescence and complication were observed.Results The recurrence rate in THP group was 17.9%,side reaction rate was 89.3%.The recurrence rate in BCG group was 16.6%,side reaction mate was 79.2%.Conclusion For efficiency,perarubicin,as well as BCG,is a safe and effect drug on preventing carcinoma of bladder postoperative recrudescence.

关 键 词：膀胱癌 吡柔吡星 膀胱灌注 

分 类 号：R737.14[医药卫生—肿瘤]