羧甲基壳聚糖的制备及其在抗菌纸中的应用  

Preparation of carboxymethyl chitosan and its application in antimicrobial paper

作　　者：马滢[1] 刘鹏涛[1,2] 刘忠[1] 

机构地区：[1]天津科技大学天津市制浆造纸重点实验室,天津300457 [2]华南理工大学制浆造纸工程国家重点实验室,广东广州510640

出　　处：《功能材料》2010年第4期648-651,共4页Journal of Functional Materials

基　　金："十一五"国家科技支撑计划课题基金资助项目(2006BAD32B07);制浆造纸工程国家重点实验室开放基金资助项目(200712);天津科技大学引进人才科研启动基金资助项目(20070417)

摘　　要：研究了在碱性条件下,用一氯乙酸对壳聚糖进行化学改性,合成了具有良好水溶性的N,O-羧甲基壳聚糖。FTIR谱图表征了其结构,证实了在N和O上均发生了取代反应。测定了产物的取代度以及抑菌性能。同时采用浆内添加法和喷淋法制得了N,O-羧甲基壳聚糖抗菌纸,并检验了其抑菌效果。To prepare good water-solubility N,O-carboxymethyl chitosan （N,O-CMCS）,chitosan was modified with monochloroacetic acid in the presence of sodium hydroxide.The structure of N,O-CMCS was characterized by FT-IR,and it was proved that substitution reaction both occurred on the N element and O element.The DS and its antimicrobial activity were studied.The preparation method （addition in pulp and insufflation） of antimicrobial paper with N,O-CMCS was also taken into consideration,and the antimicrobial activity of the prepared paper was tested.

关 键 词：壳聚糖 羧甲基壳聚糖 抗菌纸 抑菌性 

分 类 号：Q81[生物学—生物工程]