复方托吡卡胺滴眼液在近视儿童散瞳验光中的应用  

THE APPLYING OF MYDRIN-P IN MYDRIATIC OPTOMETRY OF CHILDREN WITH MYOPIA

作　　者：王雅娜[1] 董映[1] 王聪[1] 

机构地区：[1]浙江省杭州市第一人民医院眼科,浙江杭州310006

出　　处：《河北医科大学学报》2010年第4期423-424,共2页Journal of Hebei Medical University

摘　　要：目的探讨复方托吡卡胺(美多丽)滴眼液在近视儿童散瞳验光中的应用价值。方法 191例近视儿童,按年龄分为第1组即12周岁以下组(<12周岁)和第2组即12周岁以上组(≥12周岁)。第1组共88例176眼,第2组共103例206眼。先用复方托吡卡胺快速散瞳,然后进行电脑验光,1周后再用1%阿托品滴眼液滴眼3次/d,连用7 d,然后再用同一电脑验光仪验光,对比分析屈光度变化。结果第1组采用复方托吡卡胺滴眼液散瞳的验光结果球镜为(1.59±0.59)Ds;采用1%阿托品滴眼液散瞳的验光结果球镜为(1.26±0.60)Ds,两者比较差异有统计学意义(t=12.9,P<0.01);柱镜以及第2组的球镜、柱镜比较差异均无统计学意义(P>0.05)。结论对于12周岁以下的儿童,建议用1%阿托品滴眼液散瞳验光;在不适合使用阿托品滴眼液及12周岁以上的儿童,可以用复方托吡卡胺滴眼液代替1%阿托品滴眼液进行散瞳验光。Objective To study the value of the applying of Mydrin-P in mydriatic optometry of children with myopia. Methods This trial involved 88 subjects （176 eyes） who were under the age of 12 in the first group and 103 subjects （206 eyes） in the second group who were above the age of 12 with myopia. First, Mydrin-P was used to dilate pupil, and optometry by computer with TOPCON 8000 unit was performed. After 1 week, atropine gutta（1%） was applied three times daily for 7 days in succession, then optometry was conducted by the same computer. The changes of diopter were analyzed and compared. Results In the first group, there was significant difference between Mydrin-P and atropine gutta in means of the spherical lens,but no difference in the means of column lens after mydriasis. In the second group, there was no difference in the means of the spherical lens and the column lens after mydriasis. Conclusion Mydrin-P can＇t replace atropine in optometry in children under the age of 12 ,but it can replace atropine in optometry in children above the age of 12.

关 键 词：托吡卡胺 阿托品 近视 

分 类 号：R778.11[医药卫生—眼科]