CPP-ACP在正畸治疗中防治牙面脱矿的应用  

Study on application of CPP-ACP on tooth mineralization during orthodontic treatment with fixed appliance

作　　者：何文丹[1] 刘英志[1] 徐圆圆[1] 陈东[1] 

机构地区：[1]广东医学院附属深圳市第四(福田)人民医院口腔科,广东深圳518033

出　　处：《上海口腔医学》2010年第2期140-143,共4页Shanghai Journal of Stomatology

基　　金：深圳市福田区科技局基金资助项目(FTWS056)~~

摘　　要：目的:研究酪蛋白磷酸多肽-无定形磷酸钙(CPP-ACP)在固定矫治中防治牙釉质脱矿的价值。方法:选择75例接受固定矫治的正畸患者,随机分为3组:对照组交待矫治注意事项后强调牙周清洁,要求使用改良Bass法刷牙,每次刷牙时间必须超过3min,每天早晚刷牙。试验A组在对照组基础上,采用氟保护漆涂布在托糟和带环周围牙面,自然干燥。每3个月常规清洁牙面、隔湿吹干、再次均匀涂布1次。试验B组在对照组基础上,每天在托槽和带环等矫正器具的四周和牙面上涂布含有CPP-ACP的GC护牙素。临床检测指标为拆除矫治器后牙面是否有白垩色斑或齲洞,计算牙釉质脱矿指数(EDI)。采用SPSS11.0软件包对数据进行单因素方差分析。结果:对照组25例患者中,15例出现牙釉质脱矿,发生率为60%;试验A组25例患者中,9例出现牙釉质脱矿,发生率为36%;试验B组25例患者中,8例出现牙釉质脱矿,发生率为32%。观察的1632颗牙中,对照组占544颗,其中80颗出现牙釉质脱矿,发生率为14.7%;试验A组544颗,其中46颗出现牙釉质脱矿,发生率为8.46%;试验B组544颗,其中42颗出现牙釉质脱矿,发生率为7.72%。试验A组和B组的EDI比对照组减少,具有统计学意义,而两组之间的差别无统计学意义。结论:可以通过定期清洁、涂氟和护牙素等措施来减少正畸治疗中牙釉质脱矿的现象。PURPOSE：To determine the value of clinical application of CPP-ACP during orthodontic treatment with fixed appliance. METHODS：Seventy-five subjects were divided randomly into three groups,the control group ,experimental group A and experimental group B. The control group were emphasized on daily oral hygiene. Experimental group A used fluor protector every three months under the dentist＇s guidance. Experimental group B used Casein phosphopeptide amorphous calcium phosphate（CCP-ACP） once a day. After finishing the orthodontic treatment,photos were taken under the same condition ,then the degree of the enamel＇s demineralization was examined and the enamel decalcification index（EDI） was calculated. SPSS11.0 software package was used for statistical analysis. RESULTS：① The incidence of three groups＇ enamel decalcification declined in sequence as the control group （60%）,experimental group A （36%）,experimental group B （32%）. ②The incidence of the teeth＇s enamel calcification of three groups declined in sequence as the control group （14.7%）,experimental group A （8.46%）,experimental group B （7.72%）,the difference between the control group and two experimental groups was significant,while no significant difference was found between the two experimental groups. ③ EDI of the control group was 0.155±0.023,EDI of the experimental group A was 0.082± 0.009,while EDI of the experimental group B was 0.078 ±0.006. The difference between the control group and two experimental groups was statistically significant,while was not statistically significant between the two experimental groups. CONCLUSIONS：The application of fluor protector and CPP-ACP can improve the mineralization of the teeth during orthodontic treatment with fixed appliance. CPP-ACP is more convenient for the patients to use.

关 键 词：固定矫治 脱矿 涂氟 酪蛋白磷酸多肽-无定形磷酸钙 

分 类 号：R783.5[医药卫生—口腔医学]