含水率对自然关节软骨压缩变形的影响  

Effects of Hydrated Rate on Compressed Deformation of Natural Articular Cartilage

作　　者：钱善华[1,2,3] 葛世荣[1,2] 

机构地区：[1]中国矿业大学摩擦学与可靠性工程研究所,江苏徐州221116 [2]摩擦学国家重点实验室生物摩擦学中心,江苏徐州221116 [3]中国矿业大学机电工程学院,江苏徐州221116

出　　处：《航天医学与医学工程》2010年第2期122-126,共5页Space Medicine & Medical Engineering

基　　金：国家自然科学基金重点项目(50535050)

摘　　要：目的研究含水率对天然关节软骨的压缩变形特征。方法在40℃的真空恒温箱内测定纯软骨、底质骨和软骨在不同挥发时间下的质量损失,在UMT-2型试验机上测量软骨在不同含水率下的围限压缩变形,结合Mow的关节软骨本构方程,获得软骨组织的聚集模量和渗透系数。结果在40℃下纯软骨、底质骨和软骨的质量损失与挥发时间呈非线性增加,粗略确定了含水率为75%、50%、25%和0%的挥发时间分别是17min、35min、54min和100min。较高的含水率产生了较大的压缩变形、较低的聚集模量和较高的渗透系数。结论压缩变形表现了与流动有关和与流动无关的粘弹性机制,而聚集模量和渗透系数能够定量描述含水率与压缩变形之间的相互作用。Objective To study effects of hydrated rate on compressed deformation properties of natural articular cartilage.Methods The mass losses of pure cartilage,subchondral bone and cartilage sample were measured under different volatilization time with constant vacuum temperature container of 40 ℃,and confined compressed deformation of different hydrated rates was measured using UMT-2 multi-specimen test system.Combined with cartilage structural equation originated by Mow,the aggregated modulus and permeability of cartilage tissue were obtained.Results The mass losses of pure cartilage,subchondral bone and cartilage sample functioned with a non-linear ascending relation with volatilization time in the environmental temperature of 40 ℃.The volatilization time for different hydrated rates of 75%,50%,25%and 0% was 17 min,35 min,54 min and 100 min,respectively.Higher hydrated rate produced more compressed deformation,lower aggregated modulus and higher permeability.Conclusion The viscoelastic mechanisms of flow-dependence and flow-independence are manifested by compressed deformations while the aggregated modulus and permeability could quantitatively depict the mutual relation between hydrated rate and compressed deformation.

关 键 词：关节软骨 含水率 挥发时间 聚集模量 渗透性 

分 类 号：R318.08[医药卫生—生物医学工程]