零像差设计的非球面人工晶状体的临床应用研究  

Study of clinical application of aberration-free aspheric intraocular lens

作　　者：汤霞靖[1] 姚克[1] 徐雯[1] 申屠形超[1] 陈佩卿[1] 

机构地区：[1]浙江大学医学院附属第二医院眼科中心,杭州310009

出　　处：《中华眼科杂志》2010年第4期328-331,共4页Chinese Journal of Ophthalmology

摘　　要：目的比较零像差设计的非球面人工晶状体（IOL）与传统球面IOL对超声乳化白内障吸除联合IOL植入术后患者眼球差、视觉功能以及表观调节力的影响。方法采用前瞻性随机对照设计，将130例（132只眼）拟行超声乳化白内障吸除联合IOL植入术的年龄相关性白内障患者按随机数字表法分为2组，分别植入零像差设计的非球面IOL（试验组）和传统球面IOL（对照组）。术后检测IOL眼的球差、矫正远视力、矫正远视力后的近视力、对比敏感度、眩光敏感度及表观调节力；随访时间为3个月。采用χ^2检验和独立样本t检验分别对计数资料和计量资料进行统计学分析。结果术后3个月，瞳孔直径5mm情况下IOL眼的球差试验组为（0．141±0．070）μm，对照组为（0．210±0．108）μm，差异有统计学意义（t=4．365，P=0．000）。2．5°视角的对比敏感度试验组为30．62±12．50，对照组为25．92±7．36，差异有统计学意义（t=2．606，P=0．010）；眩光敏感度在4．0°、2．5°及1．6°视角上分别为31．25±8．65、26．35±8．72和12．35±4．01，显著高于对照组在相应视角上的26．70±7．98（t=3．116，P=0．002）、22．43±7．35（t=2．772，P=0．006）及9．82±4．12（t=3．553，P=0．001）；两组的矫正远视力、矫正远视力后近视力、表观调节力比较，差异均无统计学意义。结论与传统球面IOL比较，零像差的非球面IOLAkreosAO可以显著减少IOL眼的总球差，改善白内障患者术后的视觉质量，且对患者术后的表观调节力无明显影响。Objective To compare spherical aberration, visual quality and apparent accommodation between pseudophakic patients with an aberration-free aspherie intraocular lens （IOL） and patients with a spherical IOL. Methods A prospective study of 130 consecutive cases （132 eyes） was conducted. All cataract patients underwent phacoemulsification were randomized to receive an aberration-free aspheric IOL （Akreos AO, Bausch ＆ Lomb） or a spherical IOL （KS-l, Cannon Staar）. Spherical aberration of total eye, best corrected visual acuity （BCVA）, near visual acuity （NVA）, contrast sensitivity, glare sensitivity and apparent aecommodation were measured. Data were analyzed using chl-square test and independent t-test. Results The mean spherical aberration in eyes with a Tecnis IOL [ （0. 141 ±0. 070）μm] was significantly lower than that of eyes with a spherical IOL [ （0. 210 ± 0. 108 ）μm; t = 4. 365, P = 0. 000 ]. In addition, Akreos AO IOL provided a better contrast sensitivity at 2. 5° visual angle （30. 62 ± 12. 50 vs. 25. 92°7. 36; t =2.606, P=0.010）, and improved glare sensitivity at 4.0°（31.25 ±8.65 vs. 26.70 ±7.98;t =3. 116, P=0.002）, 2.5° （26.35±8.72 vs. 22.43±7.35;t =2.772, P=0.006） and 1.6° （12.35 ±4.01 vs. 9. 82 ± 4. 12; t = 3. 553, P = 0.001 ） visual angles. The difference of BCVA, NVA and apparent accommodation between these two groups was not statistically significant. Conclusion The present results demonstrated that an aberration-free aspheric IOL, Akreos AO, may reduce the spherieal aberration and improve visual performance of pseudophakic eyes and without negative influence on apparent accommodation as compare to conventional spherieal IOL .

关 键 词：晶体 人工 像差 对比敏感度 调节 眼 

分 类 号：R779.66[医药卫生—眼科]