口腔白色念珠菌与主要致龋菌相关性分析  

The correlation between oral Candida albicans and putative cariogenic bacteria.

作　　者：赵英姿[1] 宫雁冰[1] 

机构地区：[1]沈阳市口腔医院牙体牙髓科,沈阳110002

出　　处：《中国实用口腔科杂志》2010年第3期170-172,共3页Chinese Journal of Practical Stomatology

摘　　要：目的分析口腔白色念珠菌与主要致龋菌关系。方法选择2007年9—10月辽宁中医药大学职业技术学院职工和学生119人,采集其口腔牙菌斑,用PCR法检测白色念珠菌、变形链球菌和发酵乳酸杆菌阳性表达,分析其相关关系。结果白色念珠菌、变形链球菌、发酵乳酸杆菌阳性率分别为28.6%(34/119),62.2%(74/119),10.9%(13/119)。变形链球菌在白色念珠菌阳性者中检出率(16/34,47.1%)低于白色念珠菌阴性者(58/85,68.2%),差异有统计学意义,呈负相关(r=-0.197,P=0.032)。发酵乳酸杆菌在白色念珠菌阳性者中检出率与在白色念珠菌阴性者中检出率差异无统计学意义(P>0.05)。结论口腔白色念珠菌与变形链球菌可能有拮抗关系,与发酵乳酸杆菌无拮抗关系。Objective To explore the relationship between oral Candida albicans and putative cariogenic bacteria.Methods A total of 119 dental plaque samples were collected.PCR method was preformed for identification of Candida albicans,Streptococcus mutans,Lactobacillus fermentum.Analyze the correlation among them.Results The positive rate of Candida albicans,Streptococcus mutans,and Lactobacillus fermentum was 28.6%（34/119）,62.2%（74/119）and 10.9%（13/119）,respectively.The presence of Streptococcus mutans in Candida albicans carriers （47.1%,16/34）was significantly lower than non-Candida albicans carriers （68.2%,58/85）.Candida albicans carriage was negatively correlated with the presence of Streptococcus mutans （r=-0.197,P=0.032）.No correlation was found between Candida albicans carriage and Lactobacillus fermentum detected （P 0.05）.Conclusion Oral Candida albicans and Streptococcus mutans may have antagonistic relationship.

关 键 词：白色念珠菌 变形链球菌 发酵乳酸杆菌 龋病 

分 类 号：R78[医药卫生—口腔医学]