脑胶质瘤动态变化的形态学观察及其临床意义  

Dynamic morphological changes of cerebral glioma and its clinical significance

作　　者：范亦龙[1] 陈绪珠[1] 戴建平[1] 

机构地区：[1]首都医科大学附属北京天坛医院神经影像中心,北京100050

出　　处：《医学影像学杂志》2010年第4期453-456,共4页Journal of Medical Imaging

基　　金：十一五国家科技支撑计划重点项目(2007BAI05B08)资助

摘　　要：目的:总结脑胶质瘤生长、扩散趋势,为临床治疗提供参考依据。方法:选择23例经病理证实为脑胶质瘤的患者自初次发病到最后手术时的一系列MR检查,分析肿瘤初发、最后部位、生长扩散方式。结果:脑胶质瘤的生长分膨胀性(13%,3/23)和弥漫性(87%,20/23)。弥漫性生长又表现为同侧(60%,12/20)和通过胼胝体向对侧(40%,8/20)扩散。同侧扩散又分为近距离直接浸润(92%,11/12)和远隔部位的种植播散(8%,1/12)。结论:脑胶质瘤的生长扩散因侵及的纤维束不同而表现出不同的方向性,这种特点对临床治疗具有一定的参考意义。Objective：To summarize the growth and diffusion tendency of cerebral glioma and to give suggestions for clinical treatment.Methods：Twenty-three cases of cerebral gliomas were recruited in the study.All of them were proved by pathology.Analysis of the serial radiological examinations was performed from the initial to the final examination,taking into consideration of initial tumor location,final location and the dissemination tendency.Results：Cerebral glioma shows two types of growth：expansion（13%,323）and diffusion（87%,2023）.Diffusion shows two types：the contralateral（60%,1220）and ipsilateral（40%,820）.Ipsilateral diffusion still demonstrates two subtypes：infiltration to adjacent region（92%,1112）and dissemination to a remote region（8%,112）.Conclusion：The directionality of glioma growth and diffusion is variable due to the involved white matter fiber tracts.This character is helpful for clinical treatment.

关 键 词：胶质瘤 动态 生长 磁共振成像 

分 类 号：R739.4[医药卫生—肿瘤] R445.2[医药卫生—临床医学]