犬股骨髁松质骨挤压后愈合过程中骨小梁组织的形态学观察  

Morphological observation of compressed cancellous bone in femoral condyle of dog

作　　者：左艳萍[1] 汪永跃[2] 傅云婷[3] 周颖 

机构地区：[1]西安医学院口腔医学系,陕西西安710021 [2]四川大学华西口腔医学院种植科,四川成都610041 [3]深圳市龙岗中心医院口腔科,广东深圳518116 [4]成飞医院口腔科,四川成都610091

出　　处：《西安交通大学学报（医学版）》2010年第3期318-320,339,共4页Journal of Xi’an Jiaotong University（Medical Sciences）

摘　　要：目的通过建立松质骨挤压的动物模型,模拟临床种植体挤压植入术,观察松质骨挤压后愈合过程的形态学变化。方法以犬股骨髁松质骨为拟挤压部位,选择敲击挤压法,使用自行研制的挤压器,按照不同的挤压程度(0、0.6、1.22、.0 mm)进行逐级挤压、备洞,植入与种植窝直径相同的圆柱状纯钛种植体。按照不同愈合时期(1、2、4、12周)处死动物,取材,制作硬组织切片,光镜下观察松质骨骨小梁组织的形态学变化。结果挤压对于松质骨排列的影响主要表现在前四周的切片当中,种植窝壁松质骨受到挤压后,骨小梁排列更加致密。结论骨挤压技术在一定时期内能够提高种植窝周骨小梁的致密度,可能有益于提高种植体的初期稳定性。Objective This study simulated clinical implant surgery using squeeze technique by establishing a rational animal model.We investigated the microscope image in order to observe the agglutination of the cancellous bone after being compressed.Methods The cancellous bone in condyles of dog femur had been chosen as the experimental position,the implant holes were prepared using squeeze technique according to different compressing extent（0,0.6,1.2,2.0mm）,and then the corresponding implants were inserted into them.After different healing periods（1 week,2 weeks,4 weeks,12 weeks）,the mongerl dogs were sacrificed and the hard tissue slices were made,then the architecture of the cancellous bone was observed using microscope.Results The architecture of the cancellous bone was changed obviously by squeeze technique in 1 week,2 weeks and 4 weeks hard tissue slices.After being compressed,the bone trabecula around implants was compact.Conclusion The clinical implant surgery using squeeze technique helps improve peri-implant bone density,which is good for obtaining primary stabilities of implants.

关 键 词：松质骨 骨挤压 组织形态学 

分 类 号：R782[医药卫生—口腔医学]