1997年和2007年湖南地区908例原发性肺癌临床流行病学及病理特征的比较分析  

Comparative Analysis of Clinical Epidemiology and Pathological Characteristics of 908 Patients with Primary Lung Cancer of Hunan Province in 1997 and 2007

作　　者：李芳[1] 黄瓅[1] 胡成平[1] 顾其华[1] 祝小霞[1] 

机构地区：[1]中南大学湘雅医院呼吸科,长沙410007

出　　处：《中国肺癌杂志》2010年第4期326-330,共5页Chinese Journal of Lung Cancer

摘　　要：背景与目的肺癌的流行病学特征通常随时间和地区的变化而变化,此研究拟通过比较分析1997年和2007年湖南地区908例肺癌新发病例性别、年龄、城乡来源、吸烟史以及病理类型的差异,以初步了解近年来湖南地区肺癌的流行趋势。方法收集湘雅医院1997年和2007年收住的、祖居或长期居住湖南地区的908例初诊肺癌患者的临床资料并进行统计学分析。结果与1997年相比,2007年肺癌患者的男女比例由3.8:1降至2.98:1,青年肺癌患者由4.4%升至8.6%(χ2=4.465,P=0.035),农村肺癌患者由19.9%升至40.1%(χ2=30.670,P<0.001),农村肺癌患者中的吸烟者由16.9%升至39.9%(χ2=24.939,P<0.01),少见病理类型肺癌由1.3%升至4.5%(χ2=5.142,P=0.023)。结论近年来湖南地区女性、青年、农村肺癌患者以及少见病理类型肺癌比例可能有增加趋势,戒烟教育亟待加强。Background and objective Epidemiology of lung cancer will be changed along with time and region.The aim of this study is to acknowledge the tendency of primary lung cancer in hunan province in recent years by comparing and analyzing the distribution of gender,age,area,smoking and pathology of patients who were initial diagnosed lung cancer and ancestral or permanent residence of hunan province in 1997 and 2007.Methods Clinical data of 908 patients with primary lung cancer hospitalized in Xiangya hospital were collected and evaluated.Results Compared patients in 2007 with those in 1997,ratio between male and female dropped from 3.8：1 to 2.98：1,while the proportion of young patients who were under 40 years old raised from 4.4% to 8.6% （χ2=4.465,P=0.035）,patients living in the county raised from 19.9% to 40.1% （χ2=30.670,P0.001）,smoking rate of patients from county raised from 16.9% to 39.9% （χ2= 24.939,P0.01）.In addition,the proportion of rare histological types of lung cancer were also increased from 1.3% to 4.5% （χ2= 5.142,P=0.023）.Conclusion Female patients,young patients,rural patients and rare histological types of lung cancer may have a tendency of increase in hunan province in recent years,whereas smoking cessation education should be strengthened.

关 键 词：肺肿瘤 流行病学 性别 吸烟 

分 类 号：R734.2[医药卫生—肿瘤]