“即诊即治”法在宫颈高度鳞状上皮内瘤变诊治中的应用  

Clinical Application of See-and-Treat Strategy for Diagnosis and Management of High-grade Squamous Intraepithelial Lesions

作　　者：王玲[1] 吴红[1] 姚红霞[1] 徐静[1] 

机构地区：[1]同济大学附属第一妇婴保健院,上海200040

出　　处：《中国临床医学》2010年第2期284-285,共2页Chinese Journal of Clinical Medicine

基　　金：上海市浦东新区社发局项目基金资助(编号:PW2009D-8)

摘　　要：目的:探讨"即诊即治"法在宫颈高度鳞状上皮内瘤变诊治中的应用。方法:选取宫颈高度鳞状上皮内瘤变患者152例,随机分成2组:A组67例给予"三阶梯"治疗,B组85例按"即诊即治"方法治疗,比较2组患者的治疗结果。结果:A组过度治疗率为8.9%,B组为9.4%,两组比较无显著差异。Reid阴道评分高者术后宫颈上皮内瘤变(CIN)Ⅱ以上A组为62.7%、B组为61.2%。结论:"即诊即治"法治疗宫颈高度鳞状上皮内瘤变具有"三阶梯"治疗相似的治疗效果,可减少复诊,具有便捷、实用的优点。Objective：To evaluate the effectiveness between patients with high-grade squamous intraepithelial lesion（HSIL） who have undergone loop electrosurgical excisional procedure（LEEP） with and without prior colposcopically directed biopsy.Methods：There were 152 patients with cytologic HSIL who were randomly divided into eithor Group A or Group B. The 67 cases in Group A were treated by a three-step protocol,while 85 cases in Group B were treated by See and Treat protocol. The treatment efficacy of the two groups were analyzed. Results：The overtreatment rate of Group A and Group B were 8.9% and 9.4%,respectively no significant difference was found. There were 62.7% cases in Group A and 61.2% cases in Group B wih RCI high score after operation were CINⅡ or above CINⅡ. Conclusions：The colposcopically directed LEEP after a HSIL may reduce the further consultationⅡ with a similar accuracy of diagnosis compared to the standard three-step protocol,which has the advantages of convenience and utility.

关 键 词：高度鳞状上皮内瘤变 即诊即治 宫颈电圈切除术 

分 类 号：R737.33[医药卫生—肿瘤]