动脉灌注化疗与癌内注射治疗胰腺癌肝转移  

INTRA-ARTERIAL CHEMOTHERAPY PLUS INTRATUMORAL INJECTION IN THE TREATMENT OF PANCREATIC CANCER WITH LIVER METASTASIS

作　　者：彭俊平[1] 刘光中[1] 冯燮林[1] 胡勇[1] 谢昕[1] 赵京丽[1] 

机构地区：[1]四川省肿瘤医院外科,成都610041

出　　处：《肝胆外科杂志》1999年第1期37-38,共2页Journal of Hepatobiliary Surgery

摘　　要：目的探讨胰腺癌肝转移治疗的有效方法。方法采用区域性动脉灌注化疗与癌内注射疗法治疗不能切除胰腺癌肝转移的患者。结果术中癌内直接注射5─FU8例，注射无水酒精3例。术后动脉灌注化疗5─FU、DDP、ADM共25个周期。11例患者均无治疗相关并发症，平均生存期11．4±8．7（5～36）月。其中1例术后7个月再手术行胰十二指肠切除，随访29月无复发。结论该方法用于不能切除胰腺癌肝转移的治疗，有助于改善患者的生存期，是一种安全有效的方法。To discuss the effective methods of the treatment of pancreatic cancer with liver metastasis. MethodsThe patients of unresectable pancreatic cancer with liver metastasis were treated by regional intra-arterial infusion chemotherapymedicines and intra-tumor injection. Results 11 patients were treated with intra-tumor injection of 5-Fu (8 cases) or dehydrated alcohol (3 cases)in operation, and regional intra-arterial infusion chemotherapy of ADM, DDP, 5-Fu in postoperation.There were no relative compalications. The mean survival was 1. 4± 8. 7 months,ranging from 5 to 36 months. One of which was reoperated on by a radical sequential resection,there is no recurrence by follow-up 29 months in postoperation. Conclusion Thisapproach is effective and safe,and may be beneficial to those with unresectable pancreatic cancer with liver metastasis.

关 键 词：胰腺癌 肝转移瘤 动脉灌注 药物疗法 

分 类 号：R735.906[医药卫生—肿瘤] R735.705[医药卫生—临床医学]