检测AKBR和Ⅳ─C在肝癌患者手术治疗中的应用研究  

DETERMINATION OF AKBR AND SERUMⅣ-C IN PATIENTS TREATED WITH OPERATION FOR LIVERCANCER

作　　者：冉江华[1] 张家骅[1] 郭群[1] 杨炯[1] 沈浩 

机构地区：[1]昆明医学院第二附属医院肝胆外一科,昆明650101

出　　处：《肝胆外科杂志》1999年第1期43-44,共2页Journal of Hepatobiliary Surgery

摘　　要：目的探讨测定动脉血酮体比（AKBR）和血清四型胶原（Ⅳ—C）在肝癌患者手术及预后评估中的意义。方法在手术前后对20例行部分肝切除的原发性肝癌患者连续测定AKBR和血清Ⅳ—C并与术后并发症发生情况做对比。结果按术后AK－BR分成三组，A组（10例）；始终≥0．7；B组（7例）；波动在0．4和0．7之间；C组（3例）：降在0．4之下。各组并发症发生率依次为20％，42．9％，和100％。按术后Ⅳ—C分为两组：＜00μg／L的Ⅰ组中A，B，C各有8例（72.7％），3例（27.3％）和0例；≥200μg／L的Ⅱ组中A，B，C各有2例（22．2％），4例（44．4％）和3例（33．3％）。两组构成比间有显著性差异（P＜0．05）。结论：术后连续测定AKBR和Ⅳ—C有助于判断患者肝功能储备，指导治疗和评价预后。Objective to evaluate the meaning of determining arterial blood ketone body ratio and collagen type Ⅳ in patientstreated with operation for liver cancer. Mehods：before and after partial hepatoectomy, 20 patients with hepatoma were continouslystudied for their AKBR and Ⅳ-C which were in turn compared with postoperative complications. Results:Patients were classifiedinto three groups according to the value of AKBR:group A(10 cases),always above 0.7;group B (7 cases),between 0. 4 and 0. 7;group C(3 cases),below 0.4. Their complications incidence ratio were 20 %. 42. 9 %. 100%. The patients were also divided into twogroups by serum Ⅳ-C after operation:group I higher than 200μg/L decreased down below 200μg/L. There were 8 cases of A(72.7%) 、3 cases of B(27. 3%)、and 0 cases of C in group I;in group Ⅱ there were 2 cases of A(22. 2% ) .4 of B(44. 4% ) .and 3 of C(33. 3%). the proportion between two groups was significantly different. Conclusions: AKBR and serum Ⅳ-C are helpful in assessing hepatic energetic reserve and postoperative prognosis.

关 键 词：肝癌 动脉血酮体比 Ⅳ型胶原 肝功能储备 手术治疗 

分 类 号：R735.7[医药卫生—肿瘤] R657.3[医药卫生—临床医学]