2种输液方式对白血病患儿治疗期间院内感染的影响  

Influence of two kinds of infusion methods on nosocomial infection of children with leukemia during treatment progress

作　　者：余春燕[1] 黄心茹[1] 刘日阳[1] 

机构地区：[1]广东省惠州市中心人民医院,516001

出　　处：《中国实用护理杂志（中旬版）》2010年第5期36-38,共3页Chinese Journal of Practical Nursing

摘　　要：目的探讨白血病患儿治疗期间使用中心静脉导管（PICC）与植入式中心静脉输液泵（VPA）2种输液方式在院内感染方面的异同。方法2005年1月至2009年9月确诊为白血病的患儿60例，其中男35例，女25例。年龄2．0～16．5岁，平均年龄10．2岁，住院治疗期间使用PICC与VPA2种输液方式治疗，PICC组42例，住院202例次；VPA组18例，住院109例次。观察记录治疗期间所有患儿感染相关的症状及体征，常见病原菌及预后，汇总数据对照分析。结果PICC组感染相关指标如体温升高发生率较VPA组高，而C-反应蛋白升高发生率较VPA组低，差异显著，白细胞下降发生率2组比较无显著差异。感染率：PICC组为38．61％，VPA组为28．44％，2组比较差异显著，各感染部位分布2组比较有显著差异。2组痰培养、血培养主要病原菌比较无显著差异。结论2种置管方式输液均可用于治疗白血病患儿的化疗，VPA在白血病患儿中的应用院内感染的发生率较PICC低，VPA对白血病患儿化疗时可能是一种更为安全的输液置管方式。Objective To investigate the incidence of nosocomial infection of placing peripherally inserted central catheter （PICC） and venous port acess（VPA） in children with leukemia. Methods 60 cases with leukemia were treated in our hospital from January 2005 to September 2009.35 cases were mail, 25 cases were femail.Their ages ranged from 2.0 to 16.5 years old.42 cases fell to the PICC group, hospitalization for 202 times, 18 cases belonged to the VPA group, hospitalization for 109 times. The incidenee of infection in hospital, infection site, common pathogens and prognosis of two groups were analyzed retrospectively. Results The incidence of fever and increasing of C-reactive protein of the PICC group were significantly lower than those of the VPA group. There was no difference of the incidence of white blood cells decreasing between two groups. The incidence of infection in hospital in the PICC group was 38.61%, higher than 28.44% of the VPA group. Their difference was significant. There was significant difference of the distribution of infection between two groups. There was no significant difference of the major pathogens of sputum culture and blood culture between two groups. Conclusions Using venous port acess（VPA） could reduce the incidence of infection in hospital compared using peripherally insertied central catheters in children with leukemia, so venous port acess（VPA） may be safer.

关 键 词：中心静脉导管 植入式中心静脉输液泵 白血病 患儿 院内感染 

分 类 号：R781.5[医药卫生—口腔医学]