胃肠道恶性间质瘤诊治分析  

Diagnosis and treatment for gastrointestinal stromal sarcomas

作　　者：周小栋黄小娥 

机构地区：[1]余姚市人民医院外四科,浙江省余姚315400

出　　处：《中国基层医药》2010年第6期729-730,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的探讨胃肠道恶性间质瘤（GISS）的临床特点、病理学和免疫组化特点及诊断、治疗方法。方法对36例GISS患者的临床资料和诊断、治疗进行回顾性分析。结果GIST主要发生在胃和小肠，结肠和直肠较少；免疫组织化学检查显示CD117阳性33例（91．7％），CD34阳性31例（86．1％）；随访时间6-144个月，5年生存率31．8％。结论GISS是一种少见的恶性肿瘤，其确诊有赖于病理组织学和免疫组化检查，CD34和CD117阳性在诊断上有其特殊意义；手术治疗仍是主要治疗手段。Objective To explore the clinical behavior,pathological and immunohistochemical characteristics and diagnosis, treatment methods of gastrointestinal stromal sarcomas （GISS）. Methods Retrospective analysis was perfomed over 36 GISS patients based on clinical data and pathological data. Results GISS occurred more in the stomach and small intestine, than colon and rectum, lmmunohistochemieal staining showed CD117, CD34 expression, the positive rates were 91.7% and 86. 1%. Conclusion GISS is a rare malignant tumor, GISS diagnosis depends on the histologie and immunohistochemieal test. CD34 and CD117 in the positive diagnosis has its special significance, surgery is the main treatment.

关 键 词：胃肠道恶性间质瘤 诊断 治疗 

分 类 号：R735[医药卫生—肿瘤]