生物反馈治疗用于早泄的疗效比较  

Efficacy of biofeedback therapy in prmature ejaculation

作　　者：翁一鸣[1] 陈斌[1] 王鸿祥[1] 韩银发[1] 王益鑫[1] 黄翼然[1] 

机构地区：[1]上海交通大学医学院附属仁济医院泌尿外科上海市男科学研究所,上海200001

出　　处：《现代泌尿外科杂志》2010年第3期212-215,共4页Journal of Modern Urology

基　　金：上海市科学技术委员会基金(No.08411951700);上海市科委国际合作项目基金(No.08410701700)

摘　　要：目的比较生物反馈治疗联合药物治疗、单用生物反馈治疗、单用药物治疗的临床疗效。方法 60例早泄患者被随机分为3组,分别是药物组、生物反馈组和联合组。药物组予以每日西酞普兰(喜普妙)20 mg口服治疗,共治疗6周;生物组予以生物反馈治疗仪治疗,一周3次,连续治疗12次;联合组予以西酞普兰药物联合生物反馈治疗仪治疗,予以隔天下午口服20 mg喜普妙的同时,一周1次予以生物反馈治疗仪治疗,连续治疗6周。在治疗前后记录各组患者的中国早泄患者性功能评价表CIPE-5评分和射精潜伏期,比较治疗前后各组及各组间的临床疗效。结果治疗前药物组、生物反馈组和联合组的射精潜伏期分别为(0.70±0.12)(、0.66±0.16)和(0.65±0.13)min;治疗后分别为(1.14±0.75)、(1.85±0.99)和(3.09±1.34)min,与治疗前比较差异有显著的统计学意义(P<0.01)。治疗前3组的CIPE-5评分分别是(9.00±2.00)(、9.50±2.21)和(8.70±2.05)分;治疗后分别为(12.84±2.89)、(13.90±2.71)和(17.25±4.42)分,分别较治疗前差异有显著的统计学意义(P<0.01)。治疗后联合治疗组的CIPE-5评分和射精潜伏期与其余两组相比,均有显著的差异(P<0.01)。治疗6周后药物组、生物组、联合组的有效率分别为73.38%、75.00%、80.00%。结论喜普妙兰药物治疗、生物反馈治疗及生物反馈联合喜普妙药物治疗对于早泄患者射精潜伏期和CIPE-5评分均有明显提高。而三种治疗方法相比,生物反馈治疗仪联合喜普妙药物治疗有更佳的疗效。Objective To compare the efficacy of biofeedback therapy combined with drug therapy,biofeedback therapy alone and single-drug therapy. Methods 60 cases of premature ejaculation（PE） were randomly divided into 3 groups,the drug group,the biofeedback group and the combined group. The drug group took 20 mg of citalopram daily for 6 weeks, the biofeedback group received biofeedback therapy three times a week for 4 weeks, and the combined group received 20 mg of citalopram every two days with biofeedback therapy once per week for 6 weeks. The index of sexual function for PE and ejaculation latency in the vagina in each group before and after treatment were recorded and compared. Results Before the treatment,the ejaculation latency in the vagina of the three groups were （0.70 ± 0.12） ,（0.66 ± 0.16）and（0. 65 ± 0.13）min respectively,with no significant difference（P〉0.05） ,as compared with（1.14 ± 0.75）, （1.85 ± 0. 99）and（3. 09 ± 1.34）min after treatment,with significant difference（P〈0.01）. The CIPE-5 of the three groups were 9.00 ± 2.00,9.50 ± 2.21 and 8.70 ± 2.05, with no significant difference（P〉0. 05）, as compared with 12.84± 2.89,13.90 ± 2. 71 and 17. 25± 4.42 after treatment, with significant difference（P〈0.01）. The CIPE-5 score and ejaculation latency were signficantly higher in the combined group than that in the other two groups （P〈0.01）. After 6-week treatment,the effective rate was 73.38% ,75.00% and 80.00% respectively. Conclusion Citalopram therapy, biofeedback therapy and biofeedback therapy combined with citalopram treatment can markedly improve the ejaculation latency and CIPE-5 score in PE patients,among which the biofeedback therapy combined with citalopram treatment has a better effect.

关 键 词：早泄 生物反馈治疗 喜普妙 

分 类 号：R737.11[医药卫生—肿瘤]