多药耐药基因与子宫颈癌化疗  

Multi-drug resistance gene and cervix cancer chemotherapy

作　　者：李文婷[1] 王英红[1] 

机构地区：[1]石河子大学第一附属医院妇产科,新疆石河子832002

出　　处：《现代生物医学进展》2010年第7期1385-1388,共4页Progress in Modern Biomedicine

摘　　要：肿瘤细胞对化疗药物产生多药耐药性是化疗失败的主要原因之一,肿瘤多药耐药的机制十分广泛,其中P-gp/mdr1介导的多药耐药是最经典的耐药机制。故本文就MDR1与宫颈癌化疗的关系进行回顾和总结。Multi-drug resistance is one of the major obstacles to cancer chemotherapy successfully.The mechanism of multidrug resistance is vary,while the classical multidrug resistance mechanism is mediated by P-gp/mdr1.The paper was to review and summarize the relation between MDR1 and cervix cancer chemotherapy.

关 键 词：MDR1 多药耐药 子宫颈癌 化疗 

分 类 号：R730.53[医药卫生—肿瘤]