骨碱性磷酸酶在新生儿佝偻病早期诊断的临床分析  

Bone alkaline phoshpatase in early diagnosis of rachitic in neonate

作　　者：黄莹 徐爱蛟 

机构地区：[1]江西省瑞昌市人民医院,江西瑞昌332200

出　　处：《医学信息（中旬刊）》2010年第6期1354-1355,共2页Medical Information Operations Sciences Fascicule

摘　　要：目的:通过骨碱性磷酸酶的检测了解本地新生儿佝偻病的发病率与母亲妊娠的相关因素,提出干预措施。方法:用全血干化学免疫浓缩法对307例新生儿进行骨碱性磷酸酶(BALP)活性测定,采用多元线性及逐步回归法分析新生儿BALP活性水平与母亲妊娠因素的相关性。结果:受检307例,BALP=200u/L214例,200～300u/L52例,异常检出率为30.29%。结论:经临床诊断佝偻病证实,BALP检测法灵敏度、特异度、准确度高,明显优于其他方法和指标,可筛出半数以上的早期无症状佝偻病,具有良好早期诊断价值,提示临床先天性佝偻病发病率高,预防应从围产期开始,及时检测BALP水平,以便早期诊断、早期治疗。Objective：To find out the correlative factor of the incidence of rachitic in our area and the preg-nancy and on the preservative by determiny the bone alkaline phosphates（BALP）.Methods：The activity BALP of 307blessed events was measured with whole blood dry chemistry immunoconcentration.The relativity of the activity of BALP and the gravid factor with multianalysis and stepwise regressive method analysis.Results：There were214examples that BALP was less than and equal to200u/L,41examples that between200and 250u/L.And52examples that between250and300u/L.The rate of abnormity was30.29%.Conclusion：The sensitive and accuracy and-cialties of the detection in BALP confirmed good by clinic diagnosis of rachitic,superior to other methods and index.More than half of early asymptomatic rachitic can be fitrated.This indicated that the incidence of congenital rachitic was high.So that was worth diagnosing early.And the preservative should be started.In prenatal period,the BALP should be detected in time in order to diagnose early and treat early.

关 键 词：骨碱性磷酸酶 佝偻病 新生儿 相关因素 

分 类 号：R153.4[医药卫生—营养与食品卫生学]