年轻宫颈癌的临床特征与预后分析  

Analysis on clinical characteristics and prognosis of cervical cancer in young patients

作　　者：张文娟[1] 温玉库[1] 

机构地区：[1]辽宁医学院附属一院,辽宁锦州121001

出　　处：《中国妇幼保健》2010年第15期2056-2058,共3页Maternal and Child Health Care of China

摘　　要：目的:探讨年轻宫颈癌的临床特征与预后分析。方法:2001年1月～2006年12月该院共收治宫颈癌患者587例,术后均经病理证实为宫颈癌,年龄22～65岁。以其中≤35岁者67例作为研究组,并随机抽取同期>35岁的宫颈癌患者125例作为对照组,比较分析两组患者临床资料、病理分期、宫颈形态、病理分型、组织学分级、临床表现以及预后生存率等方面的差异。结果:与对照组相比,观察组初次性交<20岁、避孕药使用史、原位癌及Ⅰ期的比率明显增高,HPV感染史及Ⅱ期比率明显降低,差异均具有统计学意义(P<0.05),而两组宫颈形态、病理分型及组织学分级等方面无明显差异(P>0.05)。与此同时,观察组接触性阴道出血的比率明显提高,阴道不规则出血及白带增多的比率明显降低,差异具有统计学意义(P<0.05)。结论:加强对年轻人宫颈癌防治知识的宣传的力度,采取积极合理的宫颈癌筛查方法,早诊断、早治疗对年轻宫颈癌的防治具有重要的临床意义。Objective： To explore the clinical characteristics and prognosis of cervical cancer in young patients. Methods ： 587 patients aged 22 - 65 years old were diagnosed definitely as cervical cancer by pathological examination after operation from January 2001 to December 2006, 67 patients （ ≤35 years） were selected as study group and 125 patients were selected randomly from patients （ 〉 35 years） as control group, the clinical data, pathological stages, cervical morphology, pathological types, histological grades, clinical manifestations, prognosis and survival rate were compared between the two groups. Results： Compared with control group, the rates of first sexual intercourse ~〈20 years and application history of contraceptive drugs, incidences of carcinoma in situ and stage I in study group were significantly higher （P 〈 0. 05 ） . But there was no significant difference in cervical morphology, pathological types and histological grades between the two groups （ P 〉 0. 05 ） . At the same time, the incidence of contact vaginal bleeding in study group increased significantly, the incidences of abnormal vaginal bleeding and leucorrhea increase decreased significantly （P 〈 0. 05 ） . Conclusion： Enhancing propaganda of prevention and treatment knowledge of cervical cancer among young people, adopting active and reasonable screening method, early diagnosis and treatment are important for prevention and treatment of cervical cancer.

关 键 词：年轻宫颈癌 临床特征 预后 

分 类 号：R737.33[医药卫生—肿瘤]