利用特定引发剂制备氨甲基吡嗪  

Preparation of Aminomethyl Pyrazine by Using Specific Initiator

作　　者：苗云霞[1] 

机构地区：[1]菏泽学院化学与化工系,山东菏泽274015

出　　处：《河北化工》2010年第5期18-19,共2页Hebei Chemical Industry

摘　　要：用2-甲基吡嗪和NCS作为原料,在引发剂的引发下,经过加热、搅拌、回流等,得中间体。再加入乌洛托品,加热回流,酸化,中和,即得到较纯的氨甲基吡嗪。此方法产物较纯,效率较高,为无毒性操作。With 2 -methyl pyrazine and NCS as raw material,intermediates can be made after heating,stirring,reflux,etc.at triggerring of initiator,and then add urotropine,a more pure aminomethyl pyrazine can be got after reflux,heating,acidification and neutralisation.By this method the product is more pure,more efficient and a non-toxic operation.

关 键 词：2-甲基吡嗪 引发剂 N-氯代丁二酰亚胺(NCS) 乌洛托品 加热 回流 

分 类 号：R914.5[医药卫生—药物化学]