532例围产儿先天性畸形尸检分析  

AN ANALYSIS OF 532 AUTOPSY CASES CONCERNING PERINATAL CONGENITAL MALFORMATION

作　　者：王大亮[1] 李宝珠[1] 

机构地区：[1]北京妇产医院,邮政编码100006

出　　处：《新生儿科杂志》1999年第1期8-10,共3页The Journal of Neonatology

摘　　要：了解围产儿畸形的发生系统和畸形分配情况，为临床预防和治疗提供病理形态学依据。方法：查阅１９２９例记录完整的围产儿尸检资料，对其中５３２例先天性畸形逐一进行分类和统计学分析。结果：总尸检畸形检出率为２７．５８％，并发现畸形检出率逐年增高。畸形发生与胎儿性别无关。多系统复合畸形比例占５６．２７％；对各种畸形统计分析，以神经系统畸形的发生率为最高。结论：加强围产保健是预防诊断先天性畸形的重要手段，控制神经系统畸形发生是降低畸形发生率的重要环节。Objective To make a better understanding about the morbidity of perinatal infants congenital malformation and the number of the malformation in different systems so as to provide a patho-morphological basis for clinical prevention and treatment. Methods To consult complete perinatal infant autopsy reports of 1929 cases, among which 532 congenital malformation cases were classified and statistically analyzed one by one. Results The general discovery rate of malformation in autopsy is 27. 58%, and this rate is found out increasing year by year. The occurrence of malformation has no relation with the infants sex. The pro- portion of multi-system compound malformation makes up 56. 27% of the total. And the morbidity of malformation in the nervous system ranks the highest in the light of the statistic analysis of various malformations. Conclusions The enforcement of the perinatal care is one of the most important ways to prevent and to diagnose perinatal malformation, and the con- trol over the occurrence of nervous system malformation plays a key role in reducing the mal- formation morbidity

关 键 词：围产保健 产生率 尸检 围产儿 先天性畸形 

分 类 号：R726.204[医药卫生—儿科] R361.1[医药卫生—临床医学]