新加沙参麦冬汤联合放疗治疗中晚期非小细胞肺癌30例临床疗效观察  

Clinical observation on 30 cases of advanced stage non-small-cell lung cancer treated by integrated Xinjia Shashen Maidong Decoction and radiotherapy

作　　者：潘国凤[1] 宋巧玲[2] 吴良村[2] 

机构地区：[1]北京世纪坛医院中医科,北京100038 [2]浙江省中医院肿瘤科,杭州310006

出　　处：《中华中医药杂志》2010年第6期951-954,共4页China Journal of Traditional Chinese Medicine and Pharmacy

摘　　要：目的:评价中药复方新加沙参麦冬汤联合放疗治疗中晚期非小细胞肺癌(Non-small-cell Lung Cancer,NSCLC)的综合治疗效果。方法:选取2005年1月-2009年12月接诊的30例符合原发性支气管肺癌的诊断且经病理或细胞学诊断为Ⅲa、Ⅲb、Ⅳ期NSCLC患者,从瘤体变化、临床症状、体力状况与生存期4方面评价放疗后连续服用新加沙参麦冬汤治疗2月后的疗效。结果:按RECIST标准,患者瘤体变化评价,其有效率53.3%,稳定率86.7%;临床症状量化分级标准评价,治疗主症咳嗽有效率56.7%,缓解率93.3%;卡氏评分结果,有效率56.7%,稳定率86.7%;中位生存期11月。结论:新加沙参麦冬汤配合放疗治疗中晚期非小细胞肺癌具有一定的减毒增效作用。Objective：To estimate the clinical effect of integrated Xinjia Shashen Maidong Decoction and radiotherapy on advanced non-small-cell lung cancer （NSCLC） patients.Methods：30 NSCLC patients were treated with Xinjia Shashen Maidong Decoction after radiotherapy for more than two months,then the clinical effect were evaluated by tumor-mass stable rate,symptoms,Karnofsky score and survival period.Results：Response Evaluation Criteria in Solid Tumor （RECIST） evaluation results showed that the effective rate on relieving tumor mass was 53.3%,stable rate was 86.7%.The symptom of cough was much relieved,with 56.7% effective rate and 93.3% stable rate.And effect on Karnofsky score was good,that effective rate was 56.7% and stable rate was 86.7%. Fortunately,the patients had a median survival period of 11 months.Conclusion：Xinjia Shashen Maidong Decoction enhanced the efficacy of radiotherapy and reduced its side-effects in the treatment of advanced NSCLC patients.

关 键 词：非小细胞肺癌 中医药治疗 临床观察 

分 类 号：R734.2[医药卫生—肿瘤]