镍铬合金烤瓷修复体的生物安全性研究进展  

Biological Safety Research Progreses on Ni-Cr Alloy-porcelain Prosthesis

作　　者：杜娟[1] 张信岳[2] 

机构地区：[1]浙江省医学科学院情报研究所,杭州310013 [2]浙江省医学科学院药物研究所,杭州310013

出　　处：《医学综述》2010年第10期1512-1515,共4页Medical Recapitulate

基　　金：浙江省医药卫生科研计划项目(2008ZX005)

摘　　要：镍铬合金烤瓷修复体作为临床最常用的牙科材料,因机械刺激、腐蚀及镍离子析出引起少数机体的不良反应,包括口腔局部病变、远处皮肤病变、肾病等,并有临床安全允许范围内一定程度的细胞毒性,对受孕和胚胎发育可能也有一定的影响。但尚无足够的数据表明禁忌或严格限制使用合格的含镍铬合金的牙科材料。寻找有效的改进手段,提高其镍铬合金烤瓷修复体的抗氧化腐蚀性能,将有效提高其安全性。Ni-Cr alloy-porcelain prosthesis most commonly used as a clinical dental materials,due to mechanical stimulation,corrosion and nickel ion releasing,they caused a few adverse reactions,including local oral lesions,distant skin lesions,kidney diseases,etc.They also have some cell toxicity that within allow range for clinical safety.On pregnancy and embryonic development may also have some effect.But there is no sufficient data to show that prohibit or strictly restrict the use of nickel-chromium alloy with qualified dental materials.To find effective means to improve and enhance Ni-Cr alloy-porcelain prosthesis anti-corrosion to oxidation,will effectively enhance their safety

关 键 词：镍铬合金 牙科材料 生物安全性 

分 类 号：R78[医药卫生—口腔医学]