^(99)Tc^m-HL91与^(99)Tc^m-MIBI比较显像对甲状腺冷结节的诊断价值  

Diagnostic value of thyroid cold nodules by using ^(99)Tc^m-HL91/^(99)Tc^m-MIBI imaging

作　　者：杨帆[1] 袁卫红[1] 张怡[1] 杨建仙[1] 岳江红[1] 凌刚波[1] 

机构地区：[1]昆明医学院第二附属医院核医学科,云南昆明650101

出　　处：《中国临床医学影像杂志》2010年第5期316-318,共3页Journal of China Clinic Medical Imaging

摘　　要：目的:比较99Tcm-HL91和99Tcm-MIBI显像定性及半定量分析对甲状腺冷结节的诊断价值。方法:对103例99TcmO4-甲状腺扫描提示为冷结节的患者手术前行SPECT亲肿瘤显像,其中99Tcm-HL91显像组35例,99Tcm-MIBI显像组68例;并对两组患者早期和延迟图像的定性和半定量分析结果进行比较。结果:99Tcm-HL91乏氧显像对甲状腺冷结节诊断的准确度和特异度均高于99Tcm-MIBI亲肿瘤显像,差异有显著性(P<0.001);两种显像方法的敏感度无显著差异。结论:99Tcm-HL91乏氧显像对甲状腺冷结节良恶性的鉴别诊断更具有优越性。Objective：To evaluate the diagnostic value of ^99Tc^m-HL91 and ^99Tc^m-MIBI imaging in thyroid cold nodules with the qualitative and semi-quantitative analysis.Methods：103 patients with cold nodules underwent SPECT tumor imaging before operation.Thirty-five patients underwent 99Tcm-HL91 imaging,68 patients underwent ^99Tc^m-MIBI imaging;and then comparing the qualitative and semi-quantitative analysis of the early and delayed images in the two groups.Results：The accuracy and specificity of ^99Tc^m-HL91 hypoxia imaging in the diagnosis of thyroid cold nodules were higher than ^99Tc^m-MIBI tumor imaging,there was a significant difference（P〈0.001）;the sensitivity of the two imaging methods had no significant difference.Conclusion：^99Tc^m-HL91 imaging in differentiating malignant from benign thyroid cold nodules is more useful than ^99Tc^m-MIBI imaging.

关 键 词：甲状腺肿瘤 放射性核素显像 

分 类 号：R736.1[医药卫生—肿瘤] R817.4[医药卫生—临床医学]