脾脏窦岸细胞血管瘤一例报告及文献复习  

Littoral cell angioma of the spleen:one case report and review of literature

作　　者：王顺利 陆孝禹[2] 殷于磊[2] 肖立[2] 

机构地区：[1]上海市徐汇区大华医院病理科,上海200237 [2]复旦大学附属华东医院病理科,上海200040

出　　处：《诊断学理论与实践》2010年第2期173-176,共4页Journal of Diagnostics Concepts & Practice

摘　　要：目的:探讨脾脏窦岸细胞血管瘤(LCA)的临床病理特征和鉴别诊断。方法:对1例脾脏LCA患者的肿瘤组织进行临床病理学、免疫组化分析并复习相关文献。结果:脾脏LCA由互相吻合的血管性腔隙组成,表面衬覆单层内皮样细胞,细胞无异型,部分细胞可见嗜伊红小体,部分细胞内见含铁血黄素颗粒。免疫组化示肿瘤细胞CD8阴性(-)、CD31阳性(+)、CD34阴性(-)、溶菌酶(Lys)阳性(+)。结论:脾脏LCA是一种较少见的肿瘤,其诊断和鉴别诊断依赖于病理学检查和免疫组化标记。Objective To investigate the clinical pathological characteristics and differential diagnosis of littoral cell angioma of the spleen. Methods One case of littoral cell angioma of the spleen was analyzed by histopathology,immunohistochemistry and review of related literature. Results Littoral cell angioma of the spleen was characterized histologically by anastomosing vascular channels,which were lined with monolayer endothelioid cells with no cell atypia,some of the cells containing eosinophilic body and hemosiderin. Immunohistochemically,tumor cells were positive for CD31＋ and Lys＋,but negative for CD34 （-） and CD8（-）. Conclusions Littoral cell angioma of the spleen is a rare vascular tumor. The diagnosis and differential diagnosis of littoral cell angioma mainly rely on histopathology and immunohistochemistry examinations.

关 键 词：血管瘤 脾脏 窦岸细胞 免疫组化 

分 类 号：R733.2[医药卫生—肿瘤]