基于石墨炉原子吸收法的全血中镉的方法学研究  

Determination of cadmium in whole blood based on graphite furnace atomic absorption spectrometry

作　　者：应英[1] 冯靓[1] 汤鋆[1] 张念华[1] 马冰洁[1] 沈向红[1] 

机构地区：[1]浙江省疾病预防控制中心,杭州310009

出　　处：《中国卫生检验杂志》2010年第5期1032-1033,1106,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的:采用石墨炉原子吸收法(GFAAS)直接测定全血中的镉。方法:全血样品经2%硝酸、0.2%磷酸二氢铵混合溶液稀释后,用横向塞曼石墨炉原子吸收光谱法直接测定全血中镉。结果:对16份样本进行测定,相对标准偏差<10%,加标回收率在97%～106%之间。标准曲线在0μg/L～4μg/L范围内线性良好,方法的检出限为0.02μg/L,质控样品检测结果满意。结论:本法简便、快速、灵敏,准确度高,精密度好,适用于全血中镉的测定。Objective：To establish a method for determination of cadmium in whole blood with graphite oven atomic absorption spectrometr（GFAAS）.Methods：The samples were diluted in a medium containing 2% nitric acid and 0.2% ammonium dihydrogen phosphate before being introduced directly into the fumace and then detected by Zeeman GFAAS.Results：Determination of the sixty samples,the rate of recovery was controlled between 97% and 106% and the relative standard deviation was less than 10%.The standard curve was linear in the range of 0 μg/L～4 μg/L,the lowest detection limit was 0.02 μg/L.The mensuration result of the control samples is satisfied.Conclusion：The method is simple,rapid,accurate and of high sensitivity and precision for direct determination of cadmium in whole blood.

关 键 词：横向塞曼 GFAAS 全血 镉 

分 类 号：O657.31[理学—分析化学]