临海市2007年-2008年狂犬疫苗免疫效果监测分析  

Analysis of effect surveillance after rabies vaccine immunization from 2007 to 2008 in Linhai

作　　者：项慧[1] 徐建人[1] 

机构地区：[1]浙江省临海市疾病预防控制中心,浙江临海317000

出　　处：《中国卫生检验杂志》2010年第5期1175-1176,共2页Chinese Journal of Health Laboratory Technology

摘　　要：目的:了解我市使用的狂犬病疫苗(后简称狂苗)接种早期和全程接种后的免疫效果和安全性。方法:分别接种14天和全程接种后10天,各抽取患者静脉血5 ml,采用间接免疫荧光法(IFAT)检测中和抗体水平,抗体≥1:5为阳性,并观察疫苗接种后反应情况。结果:共采血监测308例,狂苗接种后14天抗体阳性257例,阳性率为83.4%;狂苗接种后40天检测,抗体阳性305例,阳性率为99.0%。据接种后观察,未出现严重异常反应。结论:江苏延申、武汉生物制品研究所提供的液体狂苗免疫效果及安全性比较理想,值得各地推广使用。Objective：To analyze the immunized effects after being vaccinated with rabies vaccine.Methods：IFAT was used to detect the level of antibody of Rabies 14 days after first vaccination and so was 10 days after normal process,seted antibody level 1/5 for positive,and observed the reactions after vaccination.Results：The positive rate of the former was 83.4%,and the latter was 99.0% in 308 serum samples,none of severe abnormal reactions was observed.Conclusion：The immunized effects and safty of rabies vaccine is excellent,and it is worth to be extended.

关 键 词：免疫监测 狂犬病疫苗 抗体 阳性率 

分 类 号：R186[医药卫生—流行病学]