儿童颅内肿瘤254例临床病理分析  

Intracranial tumor in children:a clinicopathologic analysis of 224 cases

作　　者：周春辉[1] 郝卓芳[1] 陆光明[1] 廖德贵[1] 黄世章[1] 

机构地区：[1]广州医学院第二附属医院病理科,广州510260

出　　处：《临床与实验病理学杂志》2010年第2期219-222,共4页Chinese Journal of Clinical and Experimental Pathology

摘　　要：目的分析儿童颅内肿瘤的临床特点和病理类型,提高儿童颅内肿瘤的早期诊断率和诊疗效果。方法对254例儿童颅内肿瘤的临床及病理资料进行总结分析。结果本组病例占我院同期脑肿瘤病例的11.70%,以男性患儿居多,占64.57%;发病年龄以9～12岁为高发,占27.95%;临床表现以头痛、头晕、呕吐为主,占73.23%;儿童颅内肿瘤以胶质细胞瘤为多见,占50.79%,其次为髓母细胞瘤,占24.42%;发病部位幕下多于幕上,占57.09%;CT检查阳性率为94.09%,MR检查阳性率为100%。结论儿童颅内肿瘤发病男多于女,肿瘤好发于幕下,以胶质瘤和髓母细胞瘤最为多见,其临床表现、发病部位、肿瘤性质和组织学类型均与成人有很大不同;影像学检查仍是目前儿童颅内肿瘤的常规检查方法,MR诊断阳性率高于CT。Purpose To analyze the clinical and pathological characteristics of intracranial tumor in children and to improve the early diagnosis rate and therapeutic effect.Methods The clinical and pathological data were collected and analyzed in 254 cases of intracranial tumor in children.Results The cases of intracranial tumor in children accounted for 11.70% of all brain tumors in our hospital in the same time.The morbidity of brain tumors was higher in males（64.57%）.The age of onset was higher in 9～12 years old（27.95%）.The most frequent initial symptoms were headache,dizziness and vomiting（73.23%）.Glioma was the most common brain tumors（50.79%） and the second was medulloblastoma（24.42%） in children.Childhood brain tumors often occurred in infratentorial region（57.09%）.The positive rate of CT and MR was 94.09% and 100%,respectively.Conclusions Childhood brain tumors are more frequently affected in males than females.They often occur in infratentorial region.Glioma and medulloblastoma are two of the most common tumors of brain in children.The clinical symptom,location,tumor property and histological types are significantly different from that in adults.CT and MR are the routine examination and the positive rate of MR is higher than that of CT in the tumor diagnosis.

关 键 词：颅内肿瘤 儿童 临床病理学 

分 类 号：R739.41[医药卫生—肿瘤]