循环肿瘤细胞研究进展  

Advances in research on circulating tumor cells

作　　者：周晴接[1] 杨建民[1] 

机构地区：[1]浙江省人民医院消化内科,浙江省杭州市310014

出　　处：《世界华人消化杂志》2010年第11期1081-1087,共7页World Chinese Journal of Digestology

基　　金：国家自然科学基金资助项目;No.30570816~~

摘　　要：循环肿瘤细胞(circulating tumor cells,CTCs)是指自发或因诊疗操作由实体瘤或转移灶释放进入外周血循环的肿瘤细胞,是恶性肿瘤患者出现术后复发和远处转移的重要原因.近年来,随着检测技术的不断改进,CTCs检测作为一种新型的非侵入性诊断工具,在早期发现患者术后复发与远处转移、评估疗效与预后等方面的应用价值已成为临床研究的热点.本文简要综述近年CTCs检测的研究进展及其临床应用状况.Circulating tumor cells （CTCs） are def ined as cells that have detached, spontaneously or as a result of clinical operations, from a primary tumor or its metastatic lesions and circulate in the peripheral blood. They are considered as the primary reason for postoperative recurrence and distant metastasis of malignant tumors. In recent years, noninvasive detection of circulating tumor cells has become a new type of diagnostic tool to evaluate postoperative recurrence, distant metastasis, and prognosis. This article reviews recent advances in research on circulating tumor cells.

关 键 词：循环肿瘤细胞 恶性肿瘤 转移 

分 类 号：R730.2[医药卫生—肿瘤]