多模式行为疗法联合氟西汀治疗强迫症的临床研究  

Multimode Behaviour Therapy Combined with Fluoxetine in the Treatment of Obsessive-Compulsive Disorder

作　　者：朱志先[1] 章华[1] 杨越秀[1] 

机构地区：[1]武汉大学人民医院临床心理科,湖北武汉430060

出　　处：《武汉大学学报（医学版）》2010年第3期401-403,共3页Medical Journal of Wuhan University

摘　　要：目的:探讨多模式行为疗法合并盐酸氟西汀治疗强迫症的疗效。方法:采用随机入组的方法,30例患者接受多模式行为疗法合并盐酸氟西汀治疗(治疗组),30例进入多模式行为治疗组(对照组)。行为治疗包括暴露与反应预防、认知重组和发展替代行为。结果:两组治疗后强迫症的症状均有显著的改善。两组对强迫行为的疗效比较无差异,而强迫思维的改善方面,多模式行为疗法合并盐酸氟西汀治疗明显优于单用多模式行为疗法,且具有更高的有效率。结论:当强迫症患者以强迫思维为主,其治疗策略应当采用行为疗法合并盐酸氟西汀。Objective： To explore the effect of combined treatment of multimode behaviour therapy（BT） and fluoxetine on obsessive-compulsive disorder.Methods： Sixty outpatients with obsessive-compulsive disorder were randomly divided into BT plus fluoxetine group（n=30） and BT group（n=30）.Multimode behaviour therapy included exposure with response prevention,cognitive restructuring and development of alternative behaviours.Results： Both groups showed a highly significant symptom reduction after treatment.There were no significant differences in compulsions between the two groups.Obsessions were significantly more reduced in the BT plus fluoxetine group than in BT group.Conclusion： The results suggest that BT should be combined with fluoxetine when obsessions dominate the clinical picture.

关 键 词：多模式行为治疗 盐酸氟西汀 强迫症 

分 类 号：R749[医药卫生—神经病学与精神病学]