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机构地区:[1]仙岳医院检验科,厦门361012 [2]厦门疾病预防控制中心,厦门361021
出 处:《中国药物滥用防治杂志》2010年第3期149-151,共3页Chinese Journal of Drug Abuse Prevention and Treatment
摘 要:目的:了解厦门地区静脉吸毒者传染病的感染状况及相关因素,为更有效地预防和控制吸毒人群传染病的感染与传播提供依据。方法:同时收集静脉吸毒者血清1036份和正常人群血清标本874份,进行肝功能、乙肝表面抗原、丙肝抗体、梅毒抗体、艾滋病抗体检测,作对比分析。结果:1036例静脉吸毒者血清标本中,肝功能异常率30.5%;乙肝表面抗原阳性率17.86%;丙肝抗体阳性率55.3%;梅毒抗体阳性率4.5%;艾滋病抗体0.68%;对照实验:874例正常人群,肝功能异常率5.1%,乙肝表面抗原阳性率10.18%,丙肝抗体阳性率2.7%,梅毒抗体阳性率0.8%,艾滋病抗体阳性率为零。两组结果对照的差异性,具有统计学意义。结论:静脉吸毒者肝功能、乙肝、丙肝、梅毒、艾滋病血清学标志物感染率明显高于正常人群,是传染病感染与传播的高危人群。吸毒者的吸毒模式和行为模式是各项传染病感染与传播的主要因素。Objective: To understand the situation and correlated factor of liver function and epidemic infected that HBV,HCV,syphilis and HIV on 1036 intravenous drug abusers (IVDAS) in Xiamen area. Meth- ods: The collected 1036 example of Application of biochemistry test that liver function and application of ELISA that HbsAg/anti-HCV/antHIVI+2/TP(RPR positive)from IVDAS, 874 serum example make contrast test from normal crowd. Results: Among 1036 IVDAS,316 (30.5%) were liver function unusual, 185 (17.86%) of HbsAg positive, 573(55.3%) of anti-HCV positive, 47(4.5%) of RPR positive, 7(0.68%) an- ti-HIVl+2 positive, Contrast experiment showed that 874 serum specimens from normal crowd 45 (5.1%) were liver function unusual, 89(10.18%) of HbsAg positive, 24(2.75%) anti-HCV positive, 13(1.49%) of RPR/TP positive, The anti-HIVl+2 all negative. There are significant difference between two samples. Conclusion: The IVDAS are easy to be infected by HBV.HCV.syphilis and HIV. Drug use and sex behavior of IVDAS are important factor.
关 键 词:静脉吸毒者 传染性疾病 感染率 相关因素 预防控制
分 类 号:R749.64[医药卫生—神经病学与精神病学] R181.3[医药卫生—临床医学]
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