甘丙肽在癫痫及癫痫持续状态患儿血浆中水平变化及意义  

Plasmatic Galanin Changes in Children with Epilepsy and Status Epilepticus

作　　者：及立立[1] 王文兰[2] 

机构地区：[1]内蒙古医学院 [2]内蒙古自治区医院儿科,内蒙古呼和浩特010017

出　　处：《内蒙古医学杂志》2010年第4期400-402,共3页Inner Mongolia Medical Journal

摘　　要：目的:探讨甘丙肽在癫痫患儿惊厥过程中的含量变化及临床意义。方法:通过酶联免疫法(ELISA)测定33例癫痫组、15例癫痫持续状态组和30例正常对照组患儿血浆甘丙肽的含量,并进行比较分析。结果:癫痫组患儿血浆甘丙肽含量明显高于癫痫持续状态组和正常对照组(F=205.911,P<0.05);癫痫持续状态组与正常对照组之间差异无统计学意义(t=0.475,P>0.05)。结论:甘丙肽在癫痫患儿惊厥过程中含量增高,表明甘丙肽与癫痫关系密切,可能起到抗惊厥的作用。Objective：To discuss the galanin content changes and clinical significance,of children with seizure in the epileptic.Method：To determine the galanin contents in plasma by enzyme-linked immunosorbent assay（ELISA）,It divide three groups,33 cases of epilepsy group、15 cases with status epilepticus group and 30 cases of normal control group.Results： Plasma of Children with epilepsy group were significantly higher than that galanin status epilepticus group and the normal control group（F=205.911,P0.05）;Status epilepticus group and normal control group,no significant difference（t=0.475,P0.05）.Conclusion： The relationship is closely between galanin and epilepsy,so galanin may play an anticonvulsant role.

关 键 词：甘丙肽 癫痫 血浆 

分 类 号：R742.1[医药卫生—神经病学与精神病学]