ARDS患者血乳酸水平与APACHEⅡ评分相关性研究  

Correlation between blood lactic acidosis levels and APACHE Ⅱ score in ARDS patients

作　　者：钟耀区[1] 吕泽峰[2] 吴思仿 林传焕 刘毅君[1] 

机构地区：[1]惠州市第三人民医院,广东惠州516002 [2]惠州市第四人民医院,广东惠州516005

出　　处：《临床和实验医学杂志》2010年第12期883-884,共2页Journal of Clinical and Experimental Medicine

摘　　要：目的观察急性呼吸窘迫综合征(ARDS)患者血乳酸水平的变化及其与急性生理学与慢性健康状况评分(APACHEII评分)的关系及意义。方法对48例ARDS患者在入住ICU24h内分别进行APACHEⅡ评分和血乳酸浓度测定,比较不同APACHEII评分分值组与血乳酸浓度。结果 APACHEII评分21～30分组血乳酸浓度明显高于11～20分组(P<0.05),APACHEII评分>30分组血乳酸浓度明显高于21～30分组(P<0.01),血乳酸水平与A-PACHEⅡ评分显著相关(r=0.682,P<0.01),死亡组血乳酸水平明显高于存活组。结论随着APACHEⅡ评分增高,血乳酸浓度也相应增高;血乳酸浓度与ARDS病情严重程度正相关,是ARDS严重程度的早期、敏感、定量的指标。Objective To observe the relationship between changes of blood lactic acidosis levels and APACHE II scores in ARDS patients.Methods APACHEⅡ score and blood lactate concentration of 48 ARDS patients were determined in the first 24 h in ICU.Results APACHEⅡscore and blood lactate concentration of 48 ARDS patients were determined in the first 24 h in ICU.Patients were divided into Group A （11～20）,Group B （21～30） and Group C （30） with different APACHE Ⅱ scores.The difference of blood lactic acidosis concentrations in the three groups was investigated.Results Blood lactic acidosis concentration of Group B was significant higher than that of Group A（P0.05）,and Group C significant higher than Group B （P0.01）.Blood lactic acidosis concentration was significantly correlated with APACHE Ⅱscore （r=0.682,P0.01）.Blood lactic acidosis concentration of death patients was significant higher than survived ones （P0.01）.Conclusion Blood lactic acidosis concentration is positively correlated with APACHE Ⅱ score,it is an early sensitive quantitative indicator of the severity in ARDS patients.

关 键 词：急性呼吸窘迫综合征 乳酸 APACHEⅡ评分 相关性 

分 类 号：R563.8[医药卫生—呼吸系统]