针吸活检对肺癌伴肺门纵隔淋巴结转移的诊断价值  

Diagnostic Value of Transbronchial Needle Aspiration and Endobronchial Ultrasoundguided Transbronchial Needle Aspiration for Hilar and Mediastinal Lymph Nodes in Lung Cancer Patients

作　　者：张嵩[1] 伊洪莉[1] 姜淑娟[1] 李元堂[2] 王永康[3] 

机构地区：[1]山东大学附属省立医院呼吸内科,济南250021 [2]山东大学附属省立医院细胞室,济南250021 [3]山东大学附属省立医院病理科,济南250021

出　　处：《中国肺癌杂志》2010年第5期447-450,共4页Chinese Journal of Lung Cancer

基　　金：山东省科技发展计划项目(No.2009GG10002061)资助~~

摘　　要：背景与目的经支气管针吸活检(transbronchial needle aspiration,TBNA)和经支气管超声引导针吸活检(endobronchial ultrasound-guided TBNA,EBUS-TBNA)是用于诊断纵隔淋巴结病变的最新检查方法。本研究旨在评价TBNA和EBUS-TBNA对肺癌伴肺门纵隔淋巴结转移的诊断价值及安全性。方法对CT检查疑似肺癌但管腔内无明显新生物且肺门纵隔淋巴结肿大的250例患者行TBNA后行活检或刷检,15例疑似肺癌患者行EBUS-TBNA。结果180例患者TBNA、刷检和活检确诊为肺癌,阳性率分别为82.86%、51.24%和45.45%。15例EBUS-TBNA的阳性率为91.67%。结论TBNA和EBUS-TBNA检查安全性好,准确率高,对肺癌伴肺门纵隔淋巴结转移的患者有较高的诊断价值。Background and objective Transbronchial needle aspiration （TBNA） and endobronchial ultrasoundguided TBNA （EBUS-TBNA） have been applied to the diagnosis for mediastinal lymph nodes. The aim of this study is to evaluate the clinical value and safety of TBNA and EBUS-TBNA on hilar and mediastinal lymph nodes of lung cancer patients. Methods Two hundred fifty patients with suspected lung cancer were enrolled. All petients with hilar and/or mediastinal lymphoadenopathy found by CT scan received TBNA, biopsy and brushing. EBUS-TBNA was performed in 15 patients among them. Results Lung cancer were confirmed in 180 patients by TBNA, biopsy and brushing. The positive rates were 82.86%, 51.24% and 45.45%. Fifteen patients after EBUS-TBNA had a positive rate of 91.67%. Conclusion TBNA and EBUS-TBNA were proved to be safe procedure with a high yield for the diagnosis of hilar and mediastinal lymph nodes in lung cancer patients.

关 键 词：经支气管针吸活检 经支气管超声引导针吸活检 淋巴结 

分 类 号：R734.2[医药卫生—肿瘤]