超声二维应变技术评价肝硬化患者右室纵向收缩功能  

Evaluation of right ventricular longitudinal contraction function in patients with liver cirrhosis using speckle tracking echocardiograohy

作　　者：徐鑫[1] 黎春雷[1] 李红洲[2] 孙杰[1] 邓又斌[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院超声影像科,武汉430030 [2]天津市人民医院影像部,天津300121

出　　处：《放射学实践》2010年第5期563-565,共3页Radiologic Practice

摘　　要：目的:应用超声二维应变技术评价肝硬化患者右室纵向收缩功能。方法:选取34例肝硬化患者作为实验组,35例健康志愿者作为对照组。常规超声心动图心尖四腔切面记录右室舒张末期横径,右房收缩期横径。记录心尖四腔切面的三个完整心动周期的高帧频二维图像,应用二维应变分析软件测量右室游离壁三个节段收缩期的峰值应变(ε),应变率(SRs)及速度(Vs)。测量右室游离壁舒张早期峰值应变率(SRe)和速度(Ve),右房收缩期峰值应变率(Sra)和速度(Va)。结果:肝硬化组右房收缩期横径较对照组增大,差异具有统计学意义(P<0.05)。肝硬化组右室游离壁三个节段的收缩期峰值应变及应变率、舒张早期峰值应变率及右房收缩期峰值应变率较对照组明显减低(P<0.05),肝硬化组右室基底段及中间段收缩期峰值及舒张早期峰值速度较对照组减低,差异具有统计学意义(P<0.005),右室心尖段收缩期峰值速度、舒张早期峰值速度及右房收缩期峰值速度较对照组减低,差异不具有统计学意义(P>0.05)。结论:超声二维应变技术可以快速准确地评价肝硬化患者右心功能,提示临床医生诊断和治疗肝硬化性心肌病以改善肝硬化患者预后。Objective：To assess the right ventricular longitudinal contraction function in patients having liver cirrhosis with 2-dimension speckle tracking echocardiograohy（STE）.Methods：34 patients with hepatic cirrhosis were selected as experimental group and 35 healthy volunteers as control group.Transverse dimension of late diastolic stage of right ventricle（RV） and systolic stage of right atrium（RA） were recorded routinely with four chamber view echocardiography.Four-chamber view of left ventricle with high frame rate two-dimensional images of three complete cycles of heart beat were recorded too,the peak strain（ε）、strain rate（SR） and velocity（V） of three segments of RV free wall in systolic stage were measured with 2-dimensional strain soft ware.The SR and V of early diastolic stage of free wall of RV and SR and V in the systolic stage of RA were measured respectively.Results：The transverse dimension in systolic stage of RA in cirrhosis patients was larger than that of control group,with significant statistical difference（P〈0.05）.The ε,SR of systolic stage and SR of early diastolic stage of free wall of RV and SR of systolic stage of RA in experimental group were markedly decreased compared with that of control group,with significant statistical differences（P〈0.05）.The peak ε of systolic stage and early diastolic stage of basal segment and middle segment of RV were reduced in experimental group compared with that of control group,with significant statistical differences（P〈0.05）.The V of systolic stage and early diastolic stage of RV and V of systolic stage of RA in experimental group were lower than that of control group,but with no statistical difference（P〉0.05）.Conclusion：The function of RV could be evaluated by STE promptly and accurately,which might remind the clinical physicians to pay attention to the possibility of cirrhotic cardiomyopathy in cirrhosis patients,early diagnosis and treatment could be achieved and prognosis could be improved.

关 键 词：超声心动图描记术 压力 肝硬化 心房功能 右 心室功能 右 

分 类 号：R575.2[医药卫生—消化系统]