急性脑梗死患者血浆同型半胱氨酸测定的意义  

Detecting the level of homocysteine in patients with acute cerebral infarction

作　　者：金梅[1] 丁蔚[1] 

机构地区：[1]泰州市人民医院检验科,江苏泰州225300

出　　处：《海南医学》2010年第11期91-92,共2页Hainan Medical Journal

摘　　要：目的观察急性脑梗死患者血浆同型半胱氨酸(Hcy)水平,探讨Hcy测定在急性脑梗死诊断、疗效观察以及早期预防中的作用。方法采用酶循环法测定76例急性脑梗死患者治疗前后和60例体检正常的健康者(对照组)血浆Hcy浓度。结果急性脑梗死组血浆Hcy含量明显高于对照组(P<0.001),差异有统计学意义。且急性脑梗死患者治疗后的血浆Hcy含量显著下降(P<0.001),差异有统计学意义。结论高同型半胱氨酸血症与急性脑梗死的发生有关,血浆同型半胱氨酸水平可以作为急性脑梗死的诊断和疗效观察的辅助指标。Objective To investigate the plasma homocysteine level in patients with acute cerebral infarction and to explore the significances of diagnosis and therapeutic effect,early prevention of acute cerebral infarction.Methods Enzymatic cycle method was applied for detecting plasma homocysteine level of 60 normal subjects and 76 cases of acute cerebral infarction patients before and after treatment.Results Plasma homocysteine level in acute cerebral infarction patient group were higher than that in control group（P〈0.001）,the difference was extremely significant.The homocysteine level decreased significantly in acute cerebral infarction patients after treatment（P〈0.001）.Conclusion Hyperhomocysteine is associated with the occurrence of acute cerebral infarction,and plasma homocysteine levels can be as the aid index for the diagnosis and therapeutic observation to acute cerebral infarction.

关 键 词：同型半胱氨酸 急性脑梗死 

分 类 号：R743.33[医药卫生—神经病学与精神病学]