西酞普兰与丙咪嗪治疗抑郁症对照研究  

A controlled study on the treatment of depression with citalopram and imipramine

作　　者：白慧丽[1] 郑素娟[1] 辛丽梅[1] 陈艳丽[1] 马杰[1] 

机构地区：[1]山东省济宁市荣复军人医院,山东济宁272101

出　　处：《中国民康医学》2010年第11期1385-1386,共2页Medical Journal of Chinese People’s Health

摘　　要：目的:探索西酞普兰与丙咪嗪治疗抑郁症的疗效与安全性。方法:选定60例符合CCMD-3诊断标准的抑郁症患者随机分为两组,分别给予西酞普兰与丙咪嗪治疗6周,用汉密尔顿抑郁量表(HAMD)评定临床疗效,用副反应量表(TESS)评定不良反应。结果:两组治疗抑郁症的疗效基本近似,西酞普兰较丙咪嗪起效快,不良反应轻。结论:西酞普兰治疗抑郁症疗效好,不良反应轻。Objective ：To explore the efficacy andside effect of citalopram and imipramine. Methods ：60patients who met CC- MD - 3 criterion for depression episode were randomly assigned to citalopram group （ n = 30 ） and imipramine group （ n = 30 ） for the treatment of 6 weeks. The clinical efficacy was evaluated by HAMD. The side effects were evaluated by TESS. Results ： There was no significant difference of the efficacy between two groups. Citalopram showed rapider efficacy and less side effects than imipramine. Con- cluslons： Citalopram showed sore efficacy and less side effects.

关 键 词：西酞普兰 丙咪嗪 抑郁症 

分 类 号：R749.41[医药卫生—神经病学与精神病学]