天智颗粒联合哈伯因治疗老年性痴呆临床观察  

Observation on the effect of combination of Tianzhi granules and Huperzine A in the elderly with Alzheimer′s disease

作　　者：杨海燕[1] 

机构地区：[1]河南中医学院第一附属医院脑病一区,郑州450000

出　　处：《中国实用神经疾病杂志》2010年第10期23-25,共3页Chinese Journal of Practical Nervous Diseases

摘　　要：目的对中药天智颗粒治疗老年性痴呆(AD)的疗效进行观察。方法采用随机对照试验的研究方法 ,对100例AD患者随机分为治疗组50例(口服天智颗粒和哈伯因),对照组50例(口服哈伯因),疗程3个月。治疗前后分别采用简易精神状态检查(MMSE)和ADL行为量表对认知功能和行为能力进行评估。结果天智颗粒和哈伯因联合治疗组患者治疗后认知、行为能力较哈伯因组改善明显(P<0.01)。结论天智颗粒和哈伯因联合治疗对老年性痴呆患者认知、行为能力有显著改善作用。Objective To investigate the effect of combination of Tianzhi granules and Huperzine A in the treatment of the elderly with Alzheimer′s disease on cognitive function and behavioral.Methods One hundred patients with Alzheimer′s disease were randomly divided into 2 groups：the group treated with Tianzhi granules and Huperzine A,control group treated with Huperzine A.MMSE scale and ADL scale of two groups were assessed and compared before treatment and 3 months after treatment.Results The cognitive function and behavioral abilities were improved markedly in the group treated with Tianzhi granules and Huperzine A （P0.01）.Conclusion Combination of Tianzhi granules and Huperzine A can markedly ameliorate the cognitive function and behavioral abilities in patients with Alzheimer′s disease.

关 键 词：天智颗粒 老年性痴呆 哈伯因 认知功能 

分 类 号：R749.16[医药卫生—神经病学与精神病学]